PROTHERICS MEDICINES DEVELOPMENT LIMITED
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Next accounts due
2027-09-30 (in 1y)
Last filed for 2025-12-31
Confirmation statement due
2027-01-26 (in 8mo)
Last made up 2026-01-12
Watchouts
None on the register
Cash
£302K
-95.2% vs 2024
Net assets
£101M
-28% vs 2024
Employees
16
+6.7% vs 2024
Profit before tax
-£22M
-180.4% vs 2024
Net assets
2-year trend · vs Industrials median
Accounts
2-year trend · latest reflected 2025-12-31
| Metric | Trend | 2024-12-31 | 2025-12-31 |
|---|---|---|---|
| Turnover | £48,204,000 | £66,830,000 | |
| Operating profit | £27,505,000 | £42,585,000 | |
| Profit before tax | £27,736,000 | -£22,310,000 | |
| Net profit | £20,839,000 | -£33,042,000 | |
| Cash | £6,275,000 | £302,000 | |
| Total assets less current liabilities | — | — | |
| Net assets | £140,001,000 | £100,833,000 | |
| Equity | £140,001,000 | £100,833,000 | |
| Average employees | 15 | 16 | |
| Wages | £1,805,000 | £1,709,000 | |
| Directors' remuneration | — | — |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. About these numbers
Year-on-year
FY2024 → FY2025 · period ending 2025-12-31 vs 2024-12-31
-
Turnover
+38.6%
£48,204,000 £66,830,000
-
Cash
-95.2%
£6,275,000 £302,000
-
Net assets
-28%
£140,001,000 £100,833,000
-
Employees
+6.7%
15 16
-
Operating profit
+54.8%
£27,505,000 £42,585,000
-
Profit before tax
-180.4%
£27,736,000 -£22,310,000
-
Wages
-5.3%
£1,805,000 £1,709,000
Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2024-12-31 | 2025-12-31 |
|---|---|---|---|
| Operating margin | 57.1% | 63.7% | |
| Net margin | 43.2% | -49.4% | |
| Current ratio | 28.97x | 33.73x |
Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.
Name history
Renamed 5 times since incorporation
- PROTHERICS MEDICINES DEVELOPMENT LIMITED 2006-06-07 → present
- PROTHERICS MOLECULAR DESIGN LIMITED 1999-12-13 → 2006-06-07
- PROTEUS MOLECULAR DESIGN LIMITED 1990-04-11 → 1999-12-13
- PROTEUS BIOTECHNOLOGY LIMITED 1987-06-22 → 1990-04-11
- PEPSITRON LIMITED 1987-05-20 → 1987-06-22
- MUSTGLEN LIMITED 1985-08-15 → 1987-05-20
Audit & accounting basis
- Accounting basis
- FRS 101
- Reporting scope
- Standalone (parent only)
- Auditor
- Kreston Reeves Audit LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“On the basis of current financial projections and cash resources and facilities available, and after making due enquiries, the directors have a reasonable expectation that the Company has adequate resources, or will be provided with adequate resources from its parent, to continue to operate for the foreseeable future. For this reason they continue to adopt the going concern basis in preparing the financial statements.”
Significant events
- “During the year the company forgave promissorry notes and other amounts due from its parent, creating an exceptional charge of £65,077,000.”
- “The audit registration of Kreston Reeves LLP was transferred to Kreston Reeves Audit LLP on 6 October 2025. Kreston Reeves Audit LLP were formally appointed as auditor to the company on 6 October 2025.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
2 active · 37 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| JENKINSON, Samuel | Director | 2022-07-01 | Oct 1976 | British |
| PATEL, Janit Vishnuprasad | Director | 2025-01-01 | Sep 1969 | British |
Show 37 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| BROWN, Vance Ronald | Secretary | 2020-02-28 | 2021-03-01 |
| DENSEM, Robert Gordon | Secretary | — | 1996-12-17 |
| JOHNSTON, Elaine Maureen | Secretary | 2019-01-11 | 2020-02-28 |
| JONES, Lygia Jane | Secretary | 2018-10-02 | 2019-01-11 |
| JONES, Lygia Jane | Secretary | 2012-02-15 | 2016-09-20 |
| MADDOX, Peter Geoffrey | Secretary | 2009-03-16 | 2012-02-15 |
| MORRIS, David Charles | Secretary | 2016-09-20 | 2018-10-02 |
| RILEY, Barrington Marshall | Secretary | 1996-12-17 | 2006-02-23 |
| VICKERS, Julie Alison | Secretary | 2006-02-23 | 2009-03-16 |
| ABOGADO NOMINEES LIMITED | Corporate Secretary | 2019-10-17 | 2021-03-01 |
| COLLYER BRISTOW SECRETARIES LIMITED | Corporate Secretary | 2021-03-01 | 2025-06-11 |
| BROWN, Vance Ronald | Director | 2020-02-28 | 2021-03-01 |
| CHRISTIE, James Campbell | Director | 1999-09-15 | 2010-12-31 |
| COTTERILL, Rodney Michael John | Director | — | 1995-03-31 |
| GARNIER, Jean | Director | — | 1995-03-31 |
| GILMORE, Kevin Michael | Director | — | 1996-03-28 |
| GRATION, David Whitnall | Director | 1997-07-29 | 1999-09-15 |
| HEATH, Andrew John William, Dr | Director | 1999-09-15 | 2008-12-04 |
| HIGHAM, Anthony | Director | 2017-12-31 | 2024-12-31 |
| JOHNSON, Peter, Dr | Director | — | 1995-03-31 |
| JOHNSTON, Elaine Maureen | Director | 2017-12-31 | 2020-02-28 |
| JONES, Stephen Jeffrey | Director | 1995-04-24 | 1996-12-16 |
| KELLEY, Peter Hudson Spence | Director | — | 1995-07-31 |
| MAKIN, Pamela Louise, Dame | Director | 2008-12-19 | 2017-12-31 |
| MARTEL, Timothy John | Director | 2017-12-31 | 2020-02-28 |
| MILLER, John Allen, Dr | Director | 1996-03-28 | 2001-07-12 |
| MONSON, Jonathan Richard | Director | 2020-02-28 | 2021-03-01 |
| POOL, John Kingston | Director | — | 1995-09-30 |
| RILEY, Barrington Marshall | Director | 1995-04-03 | 2007-08-09 |
| ROBSON, Barry, Dr | Director | — | 1995-12-31 |
| RUSHTON, Arthur, Dr | Director | 1996-09-02 | 2002-10-25 |
| SIKORSKI, Jurek Stefan | Director | 1994-06-13 | 1996-08-31 |
| SODEN, Christine Helen | Director | 2008-12-19 | 2009-03-31 |
| SODERSTROM, Rolf Kristian Berndtson | Director | 2007-08-09 | 2017-12-31 |
| THOMPSON, John Stuart | Director | — | 1995-03-31 |
| URBAIN, Jérémie Alexandre | Director | 2021-03-01 | 2024-12-31 |
| WILKINSON, Richard Brooke | Director | 2021-03-01 | 2022-06-30 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Perseus Bidco Uk Ltd | Corporate entity | Shares 75–100%, Voting 75–100%, Appoints directors | 2021-06-28 | Active |
| Btg International Healthcare Limited | Corporate entity | Shares 75–100%, Voting 75–100%, Appoints directors | 2020-07-31 | Ceased 2021-06-28 |
| Btg Management Services Limited | Corporate entity | Shares 75–100%, Voting 75–100%, Appoints directors | 2016-04-06 | Ceased 2020-07-31 |
Filing timeline
Last 20 of 279 total filings
Material constitutional events — rename, articles re-file, resolution
- 2025-05-29 RESOLUTIONS Resolution
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-04-30 | AA | accounts | Accounts with accounts type full | |
| 2026-01-16 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2026-01-09 | MR01 | mortgage | Mortgage create with deed with charge number charge creation date | |
| 2025-09-16 | MR04 | mortgage | Mortgage satisfy charge full | |
| 2025-09-16 | MR04 | mortgage | Mortgage satisfy charge full | |
| 2025-09-16 | MR04 | mortgage | Mortgage satisfy charge full | |
| 2025-09-16 | MR04 | mortgage | Mortgage satisfy charge full | |
| 2025-06-24 | TM02 | officers | Termination secretary company with name termination date | |
| 2025-05-29 | SH20 | capital | Legacy | |
| 2025-05-29 | SH19 | capital | Capital statement capital company with date currency figure | |
| 2025-05-29 | CAP-SS | insolvency | Legacy | |
| 2025-05-29 | RESOLUTIONS | resolution | Resolution | |
| 2025-04-10 | AA | accounts | Accounts with accounts type full | |
| 2025-02-14 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2025-01-09 | AP01 | officers | Appoint person director company with name date | |
| 2025-01-09 | TM01 | officers | Termination director company with name termination date | |
| 2025-01-09 | TM01 | officers | Termination director company with name termination date | |
| 2024-10-04 | MR01 | mortgage | Mortgage create with deed with charge number charge creation date | |
| 2024-08-14 | AA | accounts | Accounts with accounts type full | |
| 2024-01-29 | CS01 | confirmation-statement | Confirmation statement with no updates |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 12
- Capital events
- 2
- Officers appointed
- 0
- Officers resigned
- 1
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.