ALEX, THE LEUKODYSTROPHY CHARITY

• ◆

  5 officer resignations in last 12 months

  Multiple officers have left the board recently — see the People section for who.

Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. About these numbers

• Turnover

  -4.1%

  £741,849 → £711,107

• Cash

  -25.7%

  £293,637 → £218,270

• Net assets

  +17.9%

  £286,517 → £337,879

• Employees

  0%

  27 → 27

• Profit before tax

  +840.2%

  -£6,939 → £51,362

• Wages

  +4.4%

  £591,038 → £616,923

Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers

Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.

1. ALEX, THE LEUKODYSTROPHY CHARITY 2019-05-13 → present
2. ALD LIFE 2004-06-01 → 2019-05-13

Accounting basis

FRS 102

Reporting scope

Standalone (parent only)

Auditor

Richard Place Dobson Services Limited

Audit opinion

Unqualified (clean)

Going concern

Affirmed

“The trustees consider that there are no material uncertainties about the Charity's ability to continue as a going concern. Based on the work we have performed, we have not identified any material uncertainties relating to events or conditions that, individually or collectively, may cast significant doubt on the charity's ability to continue as a going concern for a period of at least twelve months from when the financial statements are authorised for issue.”

Significant events

• “Our efforts to improve awareness of our organisation saw the biggest year-on-year increases experienced since our humble beginnings in 2004. We welcomed 257 new beneficiaries affected by leukodystrophy, a 64% increase on the previous year.”
• “This clearly demonstrates the impact of the launch of our new website in April 2024, improvements made to online visibility and the presence of support staff at NIIS clinics.”
• “We also decided to discontinue use of X, taking the view that our values no longer aligned with the platform.”
• “Our new Grants and Trusts Fundraiser has not only increased our capacity to secure funding but has also been instrumental in a review of our impact reporting framework.”
• “Internally we promoted the Support Services Manager to Director of Support in recognition of the additional leadership duties undertaken.”
• “Leukodystrophy Awareness month doubled engagement statistics across all our social media channels (Facebook, Instagram and LinkedIn).”
• “NHSE IWMD Service and Patient Registry This vital patient service and registry continues to thrive, and as lead patient partner we play an important role in ensuring patient voice remains front and centre of service priorities. The patient registry launched in spring 2025 and will become a vital resource for researchers and decision makers in years to come.”
• “A rapid review of metachromatic leukodystrophy was announced in May 2025 and we developed a comprehensive response template for our MLD community.”
• “We continued to honour our commitment to an annual event with our 2024 event held again in Birmingham, attracting 192 attendees (a 37% year-on-year increase).”
• “Our biggest financial burden has been successive increases to minimum wage levels alongside increases to Employers' National Insurance contributions.”
• “Two of our pharmaceutical industry supporters withdrew their leukodystrophy research programmes citing poor trial results and financial issues.”
• “Staff absence due to illness contributed to a reduction in presenting opportunities for the period, and we are training additional staff members to increase our resource for these activities.”
• “unrestricted reserves were marginally below budget at year end, this represents a positive outcome in the context of rising costs and wider financial pressures across the sector.”

Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers

Filings

8

last 12 months

Capital events

0

last 24 months

Officers appointed

1

last 12 months

Officers resigned

5

last 12 months

Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.