KYOWA KIRIN INTERNATIONAL PLC
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Next accounts due
2026-06-30 (in 1mo)
Last filed for 2024-12-31
Confirmation statement due
2026-08-11 (in 3mo)
Last made up 2025-07-28
Watchouts
Cash
£4M
-99.5% vs 2023
Net assets
£783M
-34% vs 2023
Employees
89
-6.3% vs 2023
Profit before tax
-£39M
-104.1% vs 2023
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
-
3 officer resignations in last 12 months
Multiple officers have left the board recently — see the People section for who.
Net assets
2-year trend · vs Industrials median
Accounts
2-year trend · latest reflected 2024-12-31
| Metric | Trend | 2023-12-31 | 2024-12-31 |
|---|---|---|---|
| Turnover | — | — | |
| Operating profit | £92,600,000 | -£21,300,000 | |
| Profit before tax | £953,000,000 | -£38,800,000 | |
| Net profit | £948,300,000 | -£43,300,000 | |
| Cash | £737,000,000 | £3,600,000 | |
| Total assets less current liabilities | £1,190,700,000 | £817,600,000 | |
| Net assets | £1,186,300,000 | £783,000,000 | |
| Equity | £1,186,300,000 | £783,000,000 | |
| Average employees | 95 | 89 | |
| Wages | £10,700,000 | £14,400,000 | |
| Directors' remuneration | £500,000 | £700,000 |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. About these numbers
Year-on-year
FY2023 → FY2024 · period ending 2024-12-31 vs 2023-12-31
-
Turnover
—
Not reported
-
Cash
-99.5%
£737,000,000 £3,600,000
-
Net assets
-34%
£1,186,300,000 £783,000,000
-
Employees
-6.3%
95 89
-
Operating profit
-123%
£92,600,000 -£21,300,000
-
Profit before tax
-104.1%
£953,000,000 -£38,800,000
-
Wages
+34.6%
£10,700,000 £14,400,000
Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2023-12-31 | 2024-12-31 |
|---|---|---|---|
| Return on capital employed | 7.8% | -2.6% | |
| Gearing (liabilities / total assets) | 32.0% | 53.0% | |
| Current ratio | 2.20x | 0.98x | |
| Interest cover | 2.83x | -0.94x |
Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.
Name history
Renamed 3 times since incorporation
- KYOWA KIRIN INTERNATIONAL PLC 2016-02-22 → present
- PROSTRAKAN GROUP PLC 2005-03-02 → 2016-02-22
- PROSTRAKAN GROUP LIMITED 2004-10-12 → 2005-03-02
- STRAKAN GROUP LIMITED 1999-08-10 → 2004-10-12
Audit & accounting basis
- Accounting basis
- FRS 101 Reduced Disclosure Framework
- Reporting scope
- Standalone (parent only)
- Auditor
- KPMG LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“The financial statements have been prepared on a going concern basis which the directors consider to be appropriate. The KKI Group has had a balance due from its parent, KKC, at 31 December 2024 of £283m. The Directors are satisfied that the KKI Group would be able to drawdown any funding required.”
Group structure
- KYOWA KIRIN INTERNATIONAL PLC · parent
- Kyowa Kirin Holdings B.V. 100%
- Kyowa Kirin Pharmaceuticals International Limited 100%
- Kyowa Kirin Ltd* 100%
- Kyowa Kirin Pharma SAS* 100%
- Kyowa Kirin Farmaceutica S.L.U.* 100%
- Kyowa Kirin GmbH* 100%
- Kyowa Kirin Pharma B.V.* 100%
- Kyowa Kirin S.r.l.* 100%
- Kyowa Kirin AB* 100%
- Kyowa Kirin Services Ltd 100%
- Kyowa Kirin Austria GmbH* 100%
- Kyowa Kirin Pharma S.r.o.* 100%
- Kyowa Kirin Ireland Ltd* 100%
- Kyowa Kirin S.a.r.l.* 100%
- Kyowa Kirin Farmaceutica, Unipessoal 100%
- Kyowa Kirin Pharma FZ LLC* 100%
- Orchard Therapeutics North America* 100%
- Orchard Therapeutics Netherlands B.V.* 100%
- Orchard Therapeutics (Italy) S.r.l* 100%
- Orchard Therapeutics (France) SAS* 100%
- Orchard Therapeutics (Germany) GmbH* 100%
- Orchard Therapeutics (Switzerland) GmbH* 100%
- Orchard Therapeutics (Sweden) AB* 100%
- Kyowa Kirin International HoldCo Ltd 100%
- Kyowa Kirin International UK HoldCo Ltd 100%
- Kyowa Kirin International HoldCo Scotland 49%
- Kyowa Kirin International NewCo France 49%
- Kyowa Kirin International NewCo Germany 49%
- Kyowa Kirin International NewCo Spain 49%
- Kyowa Kirin International NewCo Italy 49%
Significant events
- “Operating loss for the year ended 31 December 2024 was £21.3m (2023: profit of £92.6m) with a loss on ordinary activities after taxation of £43.3m (2023: profit of £948.3m).”
- “On 5 October 2023, Kyowa Kirin Co Ltd announced the intended acquisition by KKI of Orchard Therapeutics in a deal worth $397.4m to develop several biopharmaceutical candidates in areas including oncology and autoimmune diseases. The Company successfully completed the acquisition of Orchard Therapeutics on January 24, 2024.”
- “Under the terms of the agreement, Kyowa Kirin acquired all outstanding shares of Orchard Therapeutics at a price of $16.00. Additionally, there was a contingent value right (CVR) of $1.00 per ADS, payable upon the U.S. approval of OTL-200, a gene therapy for metachromatic leukodystrophy (MLD).”
- “The US approval completed in May in 2024 resulting in consideration of $287.9m for normal stock and $20.5m for contingent value rights, resulting in total consideration of $308.5m.”
- “On 24 November 2022, the KKI Group, of which Kyowa Kirin International plc is the immediate parent company of, announced a 'Joint Venture Collaboration' ('JVC') with Grünenthal GmbH for the established medicines portfolio. The JVC includes a portfolio of brands across six therapeutic areas, with revenues primarily resulting from pain management medicines. The deal completed on 1 August 2023.”
- “In 2026, KKI has the option to dispose of its minority stake in the JVC, and sell the underlying IP.”
- “An interim dividend of £360.0m was paid during the year (2023: £nil).”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
7 active · 51 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| REISINGER, Roswitha | Secretary | 2020-03-24 | — | — |
| ARISTIDOU, Antrinkos Andrew | Director | 2020-12-01 | Jun 1968 | British |
| CARTER, Paul Rutherford | Director | 2023-04-01 | Jul 1960 | British |
| DE CRAECKER, Françoise Marie | Director | 2024-04-01 | Dec 1961 | Belgian |
| DEHAENE-PUYPE, Julie Helene Madeleine | Director | 2025-11-03 | Apr 1973 | French |
| KUNII, Daisuke | Director | 2024-01-19 | Mar 1978 | Japanese |
| OKA, Yoshiko | Director | 2026-03-19 | Feb 1970 | Japanese |
Show 51 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| MCLEAN, Andrew Firth | Secretary | 2000-01-20 | 2020-03-24 |
| WILL, James Robert | Secretary | 1999-08-10 | 2000-01-20 |
| ALLEN, Peter Vance | Director | 2005-01-01 | 2013-12-18 |
| ASBURY, Michael John, Dr | Director | 2005-03-02 | 2013-12-18 |
| BARON, Roland, Professor | Director | 2004-09-15 | 2005-12-29 |
| BENNETT, Michael Andrew | Director | 2000-02-16 | 2006-05-10 |
| BLAKE, Walter | Director | 1999-08-10 | 2000-01-20 |
| BROWN, John Robert, Dr | Director | 2014-01-01 | 2017-04-01 |
| CAWDRON, Peter Edward Blackburn | Director | 2005-07-01 | 2011-04-21 |
| CHRISTIANSEN, Claus Henrik | Director | 2000-01-20 | 2001-12-19 |
| COOK, James | Director | 2000-02-16 | 2001-06-30 |
| DOI, Kyosuke | Director | 2014-09-10 | 2019-01-28 |
| EBSWORTH, David Raymond, Dr | Director | 2017-04-01 | 2024-04-01 |
| FILDES, Francis James Thomas, Dr | Director | 2003-01-30 | 2011-04-21 |
| FILLIAS, George Gaspard | Director | 2004-12-08 | 2005-03-18 |
| FRASER, Andrew John | Director | 2004-09-15 | 2005-03-23 |
| FUJII, Hirohisa | Director | 2020-03-24 | 2023-12-31 |
| FUJII, Yasuo | Director | 2015-09-23 | 2016-09-20 |
| FUJII, Yasuo | Director | 2012-09-12 | 2014-09-10 |
| FURUYA, Yoshihiro | Director | 2020-03-24 | 2024-04-01 |
| GARDNER, Adrian David Edmund | Director | 2002-05-23 | 2007-06-29 |
| GARVEY, Paul Maurice | Director | 2007-04-16 | 2009-08-11 |
| GOODMAN, Jonathan Ross | Director | 2011-01-12 | 2011-05-17 |
| GRANATA, Francesco, Dr | Director | 2017-04-01 | 2023-03-31 |
| GRAY, Derek Richard | Director | 2000-01-20 | 2001-12-19 |
| ISHIDA, Hiroshi | Director | 2024-04-01 | 2026-03-31 |
| JENKINS, William John, Dr | Director | 2001-04-25 | 2005-03-23 |
| KANIS, John Anthony, Professor | Director | 2000-01-20 | 2005-03-23 |
| KENT, Ian Fletcher | Director | 2000-02-16 | 2000-05-31 |
| LABBE, Jean-Francois | Director | 2004-03-10 | 2005-01-31 |
| LOWCOCK, Nicholas | Director | 2001-04-25 | 2007-06-25 |
| MIKAYAMA, Toshifumi, Dr | Director | 2012-03-07 | 2023-03-24 |
| MOELLER, Gerald Heinz, Dr | Director | 2000-08-18 | 2002-03-21 |
| MORGAN, Jeremy Lewis | Director | 2023-01-03 | 2025-11-03 |
| MULLICK, Abdul Hafeez, Dr | Director | 2023-03-24 | 2025-03-19 |
| MULLICK, Abdul Hafeez | Director | 2019-01-28 | 2023-01-03 |
| O'SHEA, William James | Director | 2014-01-01 | 2017-04-01 |
| REDMOND, Michael | Director | 2001-07-17 | 2004-07-08 |
| STRATFORD, Harry Thomas, Dr | Director | 2011-07-07 | 2019-01-28 |
| STRATFORD, Harry Thomas | Director | 2000-01-20 | 2007-12-06 |
| SUDA, Toshio | Director | 2019-01-28 | 2020-03-24 |
| SUDO, Tomohiro | Director | 2025-03-19 | 2026-03-19 |
| SUDO, Tomohiro | Director | 2016-12-16 | 2020-03-24 |
| TACHIBANA, Kazuyoshi | Director | 2011-04-21 | 2012-03-07 |
| TOTTEN, Wilson, Dr | Director | 2004-09-15 | 2010-09-06 |
| TURTON, Simon, Dr | Director | 2007-06-25 | 2011-04-21 |
| TURTON, Simon, Dr | Director | 2004-09-15 | 2005-03-22 |
| WALKER, Alan Keith | Director | 2006-01-24 | 2008-01-28 |
| WATSON, Allan Mark | Director | 2009-09-09 | 2020-03-24 |
| WILL, James Robert | Nominee Director | 1999-08-10 | 2000-01-20 |
| YAMASHITA, Yoshinori | Director | 2011-04-21 | 2012-09-12 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Kyowa Kirin Co., Ltd. | Corporate entity | Shares 75–100%, Voting 75–100%, Appoints directors | 2016-04-06 | Active |
Filing timeline
Last 20 of 394 total filings
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-04-01 | AP01 | officers | Appoint person director company with name date | |
| 2026-04-01 | TM01 | officers | Termination director company with name termination date | |
| 2026-03-20 | TM01 | officers | Termination director company with name termination date | |
| 2025-11-06 | AP01 | officers | Appoint person director company with name date | |
| 2025-11-03 | TM01 | officers | Termination director company with name termination date | |
| 2025-09-01 | CH01 | officers | Change person director company with change date | |
| 2025-08-22 | CH01 | officers | Change person director company with change date | |
| 2025-08-01 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2025-07-01 | AA | accounts | Accounts with accounts type full | |
| 2025-03-26 | AP01 | officers | Appoint person director company with name date | |
| 2025-03-25 | TM01 | officers | Termination director company with name termination date | |
| 2024-08-06 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2024-07-02 | AA | accounts | Accounts with accounts type full | |
| 2024-04-12 | AP01 | officers | Appoint person director company with name date | |
| 2024-04-12 | TM01 | officers | Termination director company with name termination date | |
| 2024-04-05 | AP01 | officers | Appoint person director company with name date | |
| 2024-04-05 | TM01 | officers | Termination director company with name termination date | |
| 2024-01-22 | AP01 | officers | Appoint person director company with name date | |
| 2024-01-03 | TM01 | officers | Termination director company with name termination date | |
| 2023-08-07 | CS01 | confirmation-statement | Confirmation statement with no updates |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 9
- Capital events
- 0
- Officers appointed
- 2
- Officers resigned
- 3
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.