AVACTA LIFE SCIENCES LIMITED
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Cash
£178k
+20.3% vs 2024
Net assets
-£149m
-18.3% lowest in 3 filed years
Employees
28
-22.2% lowest in 3 filed years
Profit before tax
-£24m
-9.1% lowest in 3 filed years
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
-
Material uncertainty over going concern
As stated in Note 1, these events or conditions, along with other matters as set forth in Note 1 indicate that a material uncertainty exists that may cast significant doubt on the Company's ability to continue as a going concern. The financial statements do not include any adjustments that would be necessary if the Company were unable to continue as a going concern.
-
Going-concern uncertainty disclosed
-
Negative shareholders' funds
Net assets
3-year trend · vs Health Care median
Accounts
3-year trend · Δ = latest vs prior filed period · latest reflected 2025-12-31
| Metric | Trend | 2023-12-31 | 2024-12-31 | 2025-12-31 | Δ vs prior |
|---|---|---|---|---|---|
| Turnover | £3,704,951 | £47,151 | £0 | -100% | |
| Operating profit | -£19,143,670 | -£21,811,139 | -£23,583,058 | -8.1% | |
| Profit before tax | -£19,400,139 | -£21,777,627 | -£23,758,871 | -9.1% | |
| Net profit | -£17,348,921 | -£20,141,901 | -£23,821,347 | -18.3% | |
| Cash | £1,243,543 | £147,871 | £177,835 | +20.3% | |
| Total assets less current liabilities | -£106,466,615 | -£125,870,002 | -£148,826,954 | -18.2% | |
| Net assets | -£106,466,615 | -£125,870,002 | -£148,864,454 | -18.3% | |
| Equity | — | — | — | — | |
| Average employees | 51 | 36 | 28 | -22.2% | |
| Wages | £3,684,927 | £2,928,514 | £2,859,902 | -2.3% | |
| Directors' remuneration | — | £0 | £0 | — | |
| Directors' pension contributions | — | £0 | £0 | — |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. The Δ column is the change from the prior filed period as a percentage of |prior|; lines a company doesn't report show —. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2023-12-31 | 2024-12-31 | 2025-12-31 |
|---|---|---|---|---|
| Gearing (liabilities / total assets) | 837.1% | 1102.2% | 1246.3% | |
| Current ratio | 0.04x | 0.03x | 0.03x | |
| Interest cover | -74.64x | — | — |
Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Margin ratios are hidden where reported turnover is too small relative to profit to yield a meaningful figure — typical of holding companies whose income is mostly subsidiary dividends rather than trading revenue. Sector-distribution context coming next.
Name history
Renamed 1 time since incorporation
- AVACTA LIFE SCIENCES LIMITED 2013-03-28 → present
- APTUSCAN LIMITED 2008-05-29 → 2013-03-28
Audit & accounting basis
- Accounting basis
- FRS 102
- Reporting scope
- Standalone (parent only)
- Auditor
- BDO LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Material uncertainty disclosed
“As stated in Note 1, these events or conditions, along with other matters as set forth in Note 1 indicate that a material uncertainty exists that may cast significant doubt on the Company's ability to continue as a going concern. The financial statements do not include any adjustments that would be necessary if the Company were unable to continue as a going concern.”
Group structure
- AVACTA LIFE SCIENCES LIMITED · parent
- Affimer Limited 100%
- Avacta Life Sciences Inc. 100%
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
1 active · 10 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| COUGHLIN, Christina, Dr | Director | 2024-04-30 | Feb 1970 | American |
Show 10 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| SYKES, Timothy James | Secretary | 2012-01-10 | 2015-12-09 |
| IP2IPO SERVICES LIMITED | Corporate Secretary | 2008-05-29 | 2012-01-10 |
| DALRYMPLE, Michael Alexander, Doctor | Director | 2010-03-26 | 2012-01-10 |
| GARDINER, Tony Peter | Director | 2016-01-11 | 2024-08-29 |
| KO FERRIGNO, Paul, Dr | Director | 2008-05-29 | 2017-01-24 |
| RABBITTS, Terence Howard, Prof | Director | 2010-03-26 | 2012-01-10 |
| SLATER, Richard Craig Alan | Director | 2015-12-09 | 2016-02-01 |
| SMITH, David Alastair Maclaughlin | Director | 2012-01-10 | 2024-04-30 |
| SYKES, Timothy James | Director | 2012-01-10 | 2015-12-09 |
| IP2IPO SERVICES LIMITED | Corporate Director | 2008-05-29 | 2012-01-10 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Avacta Group Plc | Corporate entity | Shares 75–100%, Voting 75–100%, Appoints directors | 2016-04-06 | Active |
Filing timeline
Last 20 of 73 total filings
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-08-14 | AA | accounts | Accounts with accounts type full | |
| 2026-05-30 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2025-10-08 | AA | accounts | Accounts with accounts type full | |
| 2025-05-27 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2024-10-07 | TM01 | officers | Termination director company with name termination date | |
| 2024-10-04 | AD01 | address | Change registered office address company with date old address new address | |
| 2024-06-13 | AA | accounts | Accounts with accounts type full | |
| 2024-05-20 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2024-05-02 | TM01 | officers | Termination director company with name termination date | |
| 2024-05-02 | AP01 | officers | Appoint person director company with name date | |
| 2023-10-17 | AA | accounts | Accounts with accounts type full | |
| 2023-05-22 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2022-09-29 | AA | accounts | Accounts with accounts type full | |
| 2022-05-23 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2021-07-07 | AA | accounts | Accounts with accounts type full | |
| 2021-05-24 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2020-07-02 | AA | accounts | Accounts with accounts type full | |
| 2020-05-22 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2019-05-24 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2019-01-23 | AA01 | accounts | Change account reference date company current extended |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 3
- Capital events
- 0
- Officers appointed
- 0
- Officers resigned
- 0
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.