SYNTHACE LIMITED
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Next accounts due
2026-10-31 (in 5mo)
Last filed for 2025-01-31
Confirmation statement due
2026-06-05 (in 1mo)
Last made up 2025-05-22
Watchouts
None on the register
Cash
£440K
-89% lowest in 6 filed years
Net assets
-£8M
-16,512.6% vs 2024
Employees
64
-14.7% vs 2024
Profit before tax
-£10M
+11.5% vs 2024
Net assets
6-year trend · vs Health Care median
Accounts
6-year trend · latest reflected 2025-01-31
| Metric | Trend | 2020-01-31 | 2021-01-31 | 2022-01-31 | 2023-01-31 | 2024-01-31 | 2025-01-31 |
|---|---|---|---|---|---|---|---|
| Turnover | — | — | — | — | £2,506,720 | £2,877,780 | |
| Operating profit | — | — | — | — | -£11,569,963 | -£9,498,614 | |
| Profit before tax | — | — | — | — | -£11,614,207 | -£10,284,161 | |
| Net profit | — | — | — | — | -£11,720,321 | -£9,349,382 | |
| Cash | £11,671,610 | £3,303,566 | £19,202,813 | £10,716,943 | £3,998,475 | £439,512 | |
| Total assets less current liabilities | — | — | — | — | £3,310,833 | -£4,112,297 | |
| Net assets | — | — | — | — | £50,794 | -£8,336,591 | |
| Equity | — | — | — | — | £50,794 | -£8,336,591 | |
| Average employees | — | — | — | — | 75 | 64 | |
| Wages | — | — | — | — | £7,009,361 | £6,079,449 | |
| Directors' remuneration | — | — | — | — | £611,109 | £634,818 |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. About these numbers
Year-on-year
FY2024 → FY2025 · period ending 2025-01-31 vs 2024-01-31
-
Turnover
+14.8%
£2,506,720 £2,877,780
-
Cash
-89%
£3,998,475 £439,512
lowest in 6 filed years
-
Net assets
-16,512.6%
£50,794 -£8,336,591
-
Employees
-14.7%
75 64
-
Operating profit
+17.9%
-£11,569,963 -£9,498,614
-
Profit before tax
+11.5%
-£11,614,207 -£10,284,161
-
Wages
-13.3%
£7,009,361 £6,079,449
Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2020-01-31 | 2021-01-31 | 2022-01-31 | 2023-01-31 | 2024-01-31 | 2025-01-31 |
|---|---|---|---|---|---|---|---|
| Return on capital employed | — | — | — | — | -349.5% | 231.0% | |
| Current ratio | — | — | — | — | 1.89x | 0.35x | |
| Interest cover | — | — | — | — | -177.27x | -12.09x |
Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Margin ratios are hidden where reported turnover is too small relative to profit to yield a meaningful figure — typical of holding companies whose income is mostly subsidiary dividends rather than trading revenue. Sector-distribution context coming next.
Audit & accounting basis
- Accounting basis
- FRS 102
- Reporting scope
- Consolidated group
- Auditor
- Ensors
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“In auditing the financial statements, we have concluded that the directors' use of the going concern basis of accounting in the preparation of the financial statements is appropriate. Based on the work we have performed, we have not identified any material uncertainties relating to events or conditions that, individually or collectively, may cast significant doubt on the group's and parent company's ability to continue as a going concern for a period of at least twelve months from when the financial statements are authorised for issue.”
Group structure
- SYNTHACE LIMITED · parent
- Synthace Inc 100%
Significant events
- “During the year, the Group transitioned to a focus on Drug Discovery as its main market, due to the fully proven, high level of efficacy observed for Synthace software and services in this area.”
- “On 9 August 2025, a deed of variation was signed which converted all convertible loan notes into a new class of Preferred Shares.”
- “On 21 October 2025, Synthace Limited entered into an agreement to surrender its old leased premises and enter into a new lease agreement.”
- “On 3 July 2025, Synthace Limited signed a term sheet to issue 69,124,420 ordinary series "AA" shares at \u00a30.0434 per share, for total consideration of \u00a33,000,000.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
3 active · 18 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| BARALT, Willem George | Director | 2024-02-28 | Nov 1968 | Dutch |
| GERSHATER, Markus Christian, Dr | Director | 2019-04-08 | Jun 1980 | British |
| THEURILLAT, Jacques, Mr. | Director | 2025-08-11 | Mar 1959 | Swiss |
Show 18 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| MALIN, Jonathan Adam | Secretary | 2018-04-26 | 2020-06-16 |
| BOBANOVIC, Josko | Director | 2020-12-04 | 2022-01-12 |
| BOBANOVIC, Josko | Director | 2013-08-13 | 2019-12-04 |
| BURT, Thomas Henry | Director | 2021-11-12 | 2023-08-21 |
| DEIESO, Donald, Dr | Director | 2022-08-18 | 2023-05-03 |
| DOBBIE, Alexander Archibald | Director | 2014-07-08 | 2017-08-31 |
| ELEFTHERIOU, Michail | Director | 2012-04-12 | 2013-08-13 |
| FELL, Timothy Stephen | Director | 2013-02-11 | 2021-05-24 |
| FOX, Isabel | Director | 2017-09-29 | 2020-12-04 |
| GERSHATER, Markus Christian | Director | 2011-05-31 | 2013-08-13 |
| LEVY-YURISTA, Guy | Director | 2021-05-24 | 2024-10-29 |
| LIAO, Bill | Director | 2015-01-05 | 2018-12-04 |
| LIAO, William Fu Wei | Director | 2019-12-04 | 2022-01-12 |
| MIKATI, Sami | Director | 2012-04-12 | 2017-08-05 |
| SHIFF, Susan Patricia, Dr | Director | 2018-06-05 | 2025-08-11 |
| WARD, Sean Michael | Director | 2011-05-31 | 2019-02-01 |
| WIEDERHOLD, Robert Peter | Director | 2018-03-13 | 2022-02-17 |
| ZHANG, Haorui "Patrick" | Director | 2018-12-04 | 2025-08-11 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Sofinnova Crossover I Slp | Corporate entity | Shares 25–50%, Voting 25–50% | 2025-08-11 | Active |
| Sofinnova Green Seed Fund | Corporate entity | Shares 25–50%, Voting 25–50% | 2016-06-01 | Ceased 2017-09-21 |
Filing timeline
Last 20 of 190 total filings
Material constitutional events — rename, articles re-file, resolution
- 2025-09-23 MA Memorandum articles
- 2025-09-23 RESOLUTIONS Resolution
- 2025-09-12 RP04SH01 Legacy PDF
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-05-01 | SH01 | capital | Capital allotment shares | |
| 2026-04-08 | RP01SH01 | miscellaneous | Legacy | |
| 2026-03-30 | SH01 | capital | Capital allotment shares | |
| 2026-02-17 | AA | accounts | Accounts with accounts type group | |
| 2025-12-16 | SH01 | capital | Capital allotment shares | |
| 2025-09-23 | MA | incorporation | Memorandum articles | |
| 2025-09-23 | RESOLUTIONS | resolution | Resolution | |
| 2025-09-16 | SH10 | capital | Capital variation of rights attached to shares | |
| 2025-09-16 | SH10 | capital | Capital variation of rights attached to shares | |
| 2025-09-16 | SH10 | capital | Capital variation of rights attached to shares | |
| 2025-09-16 | SH10 | capital | Capital variation of rights attached to shares | |
| 2025-09-15 | SH10 | capital | Capital variation of rights attached to shares | |
| 2025-09-15 | SH08 | capital | Capital name of class of shares | |
| 2025-09-12 | PSC02 | persons-with-significant-control | Notification of a person with significant control | |
| 2025-09-12 | PSC09 | persons-with-significant-control | Withdrawal of a person with significant control statement | |
| 2025-09-12 | RP04SH01 | change-of-name | Legacy | |
| 2025-09-08 | SH01 | capital | Capital allotment shares | |
| 2025-09-08 | AP01 | officers | Appoint person director company with name date | |
| 2025-09-05 | TM01 | officers | Termination director company with name termination date | |
| 2025-09-05 | TM01 | officers | Termination director company with name termination date |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 20
- Capital events
- 10
- Officers appointed
- 1
- Officers resigned
- 2
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.