OXFORD SCIENCE ENTERPRISES PLC
Oxford Science Enterprises PLC is an unlisted public company operating as an early-stage venture capital firm and venture builder that partners with the University of Oxford to commercialise academic research and fund spin-out businesses across the deep tech, life sciences, and healthtech sectors.
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Cash
£241M
+31.6% vs 2024
Net assets
£1.3B
+16.9% highest in 3 filed years
Employees
78
+16.4% highest in 3 filed years
Profit before tax
£183M
+413.9% highest in 3 filed years
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
-
Confirmation statement overdue
Due 2026-07-03.
Profit before tax
3-year trend · vs Financials median
Accounts
3-year trend · Δ = latest vs prior filed period · latest reflected 2025-12-31
| Metric | Trend | 2023-12-31 | 2024-12-31 | 2025-12-31 | Δ vs prior |
|---|---|---|---|---|---|
| Turnover | £6,475,000 | £4,958,000 | £5,051,000 | +1.9% | |
| Operating profit | -£31,333,000 | -£58,269,000 | £183,816,000 | +415.5% | |
| Profit before tax | -£131,665,000 | -£58,269,000 | £182,884,000 | +413.9% | |
| Net profit | -£131,665,000 | -£58,269,000 | £182,884,000 | +413.9% | |
| Cash | £262,128,000 | £183,063,000 | £240,923,000 | +31.6% | |
| Total assets less current liabilities | — | £1,133,931,000 | £1,402,669,000 | +23.7% | |
| Net assets | — | — | — | — | |
| Equity | £1,139,664,000 | £1,081,472,000 | £1,264,356,000 | +16.9% | |
| Average employees | 77 | 67 | 78 | +16.4% | |
| Wages | £7,070,000 | £8,861,000 | £9,887,000 | +11.6% | |
| Directors' remuneration | £1,900,000 | £2,700,000 | £2,700,000 | 0% |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. The Δ column is the change from the prior filed period as a percentage of |prior|; lines a company doesn't report show —. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2023-12-31 | 2024-12-31 | 2025-12-31 |
|---|---|---|---|---|
| Return on capital employed | — | -5.1% | 13.1% | |
| Current ratio | 3.02x | 4.57x | 2.19x | |
| Interest cover | -23.97x | -46.65x | 21.19x |
Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Margin ratios are hidden where reported turnover is too small relative to profit to yield a meaningful figure — typical of holding companies whose income is mostly subsidiary dividends rather than trading revenue. Sector-distribution context coming next.
Name history
Renamed 2 times since incorporation
- OXFORD SCIENCE ENTERPRISES PLC 2021-09-30 → present
- OXFORD SCIENCES INNOVATION PLC 2015-03-17 → 2021-09-30
- OXFORD SCIENCES PLC 2014-06-19 → 2015-03-17
Audit & accounting basis
- Accounting basis
- IFRS
- Reporting scope
- Consolidated group
- Auditor
- Deloitte LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“Based on the work we have performed, we have not identified any material uncertainties relating to events or conditions that, individually or collectively, may cast significant doubt on the Group's and parent company's ability to continue as a going concern for a period of at least twelve months from when the financial statements are authorised for issue.”
Group structure
- OXFORD SCIENCE ENTERPRISES PLC · parent
- OSI Services Limited 100%
- OSI Midco Limited
- Oxford Science Enterprises Holdings Limited 100%
- Oxford Sciences Enterprises II Limited 100%
- OSI Services Limited Support 100%
- OSI Labs Limited 100%
- OSE Manager 100%
Significant events
- “During the year we completed two significant exits: the $1.075bn exit of Oxford Ionics to IonQ and the sale of DBT to Amgen for a total consideration of up to $840m ($80m upfront).”
- “Developed an AI & tech strategy to drive more efficient and scalable operations, with Phase 1 launched in 2026.”
- “Oxford Ionics exit is just the beginning. We have a pipeline of exciting companies emerging, each rooted in Oxford’s extraordinary research base and nurtured through our venture-building approach.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
12 active · 18 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| BLAKEMAN, Athene Eliana Georgina | Secretary | 2022-01-25 | — | — |
| PINSENT MASONS SECRETARIAL LIMITED | Corporate Secretary | 2015-04-09 | — | — |
| BRUNT, Andre Crawford | Director | 2020-02-14 | Mar 1971 | British |
| BUSSEY, Edward Martin | Director | 2023-09-01 | Oct 1967 | British |
| CHAMBERS, Christopher Michael | Director | 2015-06-01 | Jun 1961 | British |
| DONNELLY, Peter James, Professor | Director | 2024-01-30 | May 1959 | British,Australian |
| EDMONDSON, Jack Cemlyn | Director | 2023-09-01 | Aug 1977 | British |
| HOBBS, Frederick David Richard, Professor | Director | 2025-11-21 | Nov 1953 | British |
| JENKINSON, Antonia Scarlett | Director | 2026-04-28 | Jul 1969 | British |
| MURRAY, Fiona Elizabeth | Director | 2024-05-14 | May 1968 | British |
| STEVENS, Molly Morag | Director | 2026-01-01 | May 1974 | British |
| TAYLOR, Bernard John | Director | 2015-06-01 | Nov 1956 | British |
Show 18 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| O'BRIEN, Kate | Secretary | 2019-06-13 | 2021-09-23 |
| SINGH, Benjamin Dhian | Secretary | 2014-06-19 | 2015-04-09 |
| WILKINSON, James Henry | Secretary | 2021-09-23 | 2022-01-25 |
| AUBREY, Alan John | Director | 2015-06-01 | 2021-10-01 |
| BELL, John Irving, Professor Sir | Director | 2015-06-01 | 2023-02-28 |
| BODDIE, Simon | Director | 2021-11-15 | 2026-01-31 |
| CASTELL, William, Sir | Director | 2016-03-03 | 2016-08-31 |
| CONN III, Charles Ronald | Director | 2019-03-04 | 2020-02-04 |
| DAVIES, Peter Graham | Director | 2015-07-01 | 2021-10-01 |
| DORMANDY, Alexis Paul Momtchiloff | Director | 2020-10-16 | 2022-12-12 |
| KERR, Giles | Director | 2015-06-01 | 2021-10-01 |
| KHAN, Aneeqa | Director | 2019-03-13 | 2021-12-31 |
| LAXER, Richard Alan | Director | 2022-04-01 | 2024-01-31 |
| NORWOOD, David Robert | Director | 2014-06-19 | 2019-01-31 |
| PICHETTE, Patrick, Mr. | Director | 2019-03-05 | 2020-01-30 |
| PRESTON, Heather Elizabeth, Dr | Director | 2021-11-15 | 2023-12-31 |
| SNOW, Alexander Charles Wallace | Director | 2014-06-19 | 2017-05-02 |
| WILKINSON, James Henry | Director | 2015-11-17 | 2026-03-31 |
Ownership
Persons with significant control
Filing timeline
Last 20 of 146 total filings
Material constitutional events — rename, articles re-file, resolution
- 2025-07-14 RESOLUTIONS Resolution
- 2024-07-16 RESOLUTIONS Resolution
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-05-21 | AA | accounts | Accounts with accounts type group | |
| 2026-05-11 | AP01 | officers | Appoint person director company with name date | |
| 2026-04-07 | TM01 | officers | Termination director company with name termination date | |
| 2026-02-02 | TM01 | officers | Termination director company with name termination date | |
| 2026-01-26 | AP01 | officers | Appoint person director company with name date | |
| 2025-11-21 | AP01 | officers | Appoint person director company with name date | |
| 2025-09-29 | MR01 | mortgage | Mortgage create with deed with charge number charge creation date | |
| 2025-07-14 | RESOLUTIONS | resolution | Resolution | |
| 2025-06-23 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-05-06 | AA | accounts | Accounts with accounts type full | |
| 2025-04-16 | SH08 | capital | Capital name of class of shares | |
| 2025-04-01 | MR01 | mortgage | Mortgage create with deed with charge number charge creation date | |
| 2024-07-16 | RESOLUTIONS | resolution | Resolution | |
| 2024-07-04 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2024-05-21 | AP01 | officers | Appoint person director company with name date | |
| 2024-04-26 | AA | accounts | Accounts with accounts type full | |
| 2024-03-26 | SH01 | capital | Capital allotment shares | |
| 2024-02-13 | AP01 | officers | Appoint person director company with name date | |
| 2024-02-13 | TM01 | officers | Termination director company with name termination date | |
| 2024-01-31 | TM01 | officers | Termination director company with name termination date |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 8
- Capital events
- 1
- Officers appointed
- 3
- Officers resigned
- 2
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.