F-STAR THERAPEUTICS LIMITED
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Next accounts due
2027-09-30 (in 1y)
Last filed for 2025-12-31
Confirmation statement due
2026-09-06 (in 4mo)
Last made up 2025-08-23
Watchouts
Cash
£6M
+1,591.1% vs 2024
Net assets
£15M
+469.1% vs 2024
Employees
24
-31.4% vs 2024
Profit before tax
£10M
+195.8% vs 2024
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
-
1 PSC ceased in last 24 months
Significant control changed hands — see the Ownership section.
Net assets
2-year trend · vs Health Care median
Accounts
2-year trend · latest reflected 2025-12-31
| Metric | Trend | 2024-12-31 | 2025-12-31 |
|---|---|---|---|
| Turnover | £11,145,948 | £4,532,865 | |
| Operating profit | £3,984,739 | -£5,392,435 | |
| Profit before tax | £3,538,383 | £10,465,531 | |
| Net profit | £3,538,383 | £10,338,525 | |
| Cash | £330,794 | £5,594,179 | |
| Total assets less current liabilities | -£2,534,550 | £15,137,200 | |
| Net assets | -£4,101,325 | £15,137,200 | |
| Equity | -£4,101,325 | £15,137,200 | |
| Average employees | 35 | 24 | |
| Wages | £3,370,360 | £4,241,256 | |
| Directors' remuneration | £1,494,495 | £1,871,731 |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. About these numbers
Year-on-year
FY2024 → FY2025 · period ending 2025-12-31 vs 2024-12-31
-
Turnover
-59.3%
£11,145,948 £4,532,865
-
Cash
+1,591.1%
£330,794 £5,594,179
-
Net assets
+469.1%
-£4,101,325 £15,137,200
-
Employees
-31.4%
35 24
-
Operating profit
-235.3%
£3,984,739 -£5,392,435
-
Profit before tax
+195.8%
£3,538,383 £10,465,531
-
Wages
+25.8%
£3,370,360 £4,241,256
Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2024-12-31 | 2025-12-31 |
|---|---|---|---|
| Operating margin | 35.8% | -119.0% | |
| Net margin | 31.7% | 228.1% | |
| Return on capital employed | -157.2% | -35.6% | |
| Gearing (liabilities / total assets) | 127.0% | 7.7% | |
| Current ratio | 0.65x | 12.68x | |
| Interest cover | 1.15x | -6.28x |
Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.
Audit & accounting basis
- Accounting basis
- IFRS
- Reporting scope
- Standalone (parent only)
- Auditor
- Ensors
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“For the financial year ended December 31, 2025, the Company reported an operating loss of 5.4 million GBP. Following the successful transition to a standalone entity independent of its former parent, management have conducted a rigorous assessment of the Company's liquidity and capital structure. This assessment included a comprehensive review of the 2026-2027 Budgeted Forecasts, which incorporate projected R&D expenditure, intellectual property maintenance, and anticipated milestone inflows from pharmaceutical partners. Based on these projections and the Company's current cash position, the Directors have a reasonable expectation that F-star Therapeutics Ltd has adequate resources to continue in operational existence for the foreseeable future. Accordingly, the Company continues to adopt the going-concern basis in preparing the financial statements.”
Significant events
- “In April 2025, F-star Therapeutics Limited was acquired by Keystone Capital 814, LLC, a U.S based investment company.”
- “Following the acquisition, the company has severed its ties from its immediate parent company FTI (F-star Therapeutics, Inc), and is also no longer linked to invoX Pharma Limited ('invoX'), a U.K. based wholly-owned subsidiary of Sino Biopharmaceutical Limited ('Sino') (HKEK 1177 HK).”
- “In the final quarter for 2025, the F-star Board made the strategic decision to stop all in-house drug discovery, close the Cambridge facility and concentrate on managing existing relationships with pharmaceutical partners and focused business development with potential new partners.”
- “The company has terminated its office lease in December 2025.”
- “All amounts owed to parent undertaking are settled on March 25, 2025 ahead of sale of shares to Keystone Capital 814 LLC.”
- “On June 22, 2022, the company's immediate and ultimate parent FTI announced a proposed acquisition by invoX... The transaction completed on March 8, 2023... Following the acquisition by invoX, the net assets relating to F-star's clinical business were transferred to invoX. F-star's clinical operations transferred to invoX on June 1, 2023. The final phase of the clinical transfer took place on February 1, 2024.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
2 active · 17 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| BREWIS, Neil Douglas, Dr | Director | 2023-03-08 | Jul 1966 | British |
| LASH, John Edward | Director | 2025-04-02 | Mar 1986 | American |
Show 17 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| FITZPATRICK, John Paul | Secretary | 2020-04-29 | 2021-05-13 |
| HASSAN, Tolga | Secretary | 2019-05-07 | 2020-04-30 |
| TAYLOR WESSING SECRETARIES LIMITED | Corporate Secretary | 2019-05-07 | 2019-11-27 |
| BENZ JR, Edward John | Director | 2019-12-18 | 2020-11-20 |
| BERMINGHAM, Nessan Anthony | Director | 2019-05-07 | 2020-11-20 |
| BREWIS, Neil Douglas, Dr | Director | 2021-11-26 | 2023-03-08 |
| EDWARDS, John Blodgett | Director | 2019-05-07 | 2019-12-18 |
| FIEHLER, Ryan William | Director | 2025-04-02 | 2025-12-01 |
| FITZPATRICK, John Paul | Director | 2020-11-20 | 2021-04-01 |
| FORMELA, Jean-Francois, Dr | Director | 2019-05-07 | 2020-11-20 |
| FORSTER, Eliot Richard | Director | 2019-05-07 | 2023-03-08 |
| HARLAND, Deborah, Dr | Director | 2019-05-07 | 2020-11-20 |
| HASSAN, Tolga | Director | 2018-08-22 | 2019-12-18 |
| KROL, Patrick Johan Hendrik | Director | 2019-05-07 | 2020-11-20 |
| RACE, Geoffrey Robin | Director | 2019-12-18 | 2020-11-20 |
| RUKER, Florian, Dr | Director | 2019-05-07 | 2019-12-18 |
| SCHUEHSLER, Helmut | Director | 2019-05-07 | 2020-11-20 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| John Edward Lash | Individual | Shares 75–100%, Voting 75–100%, Appoints directors | 2025-04-02 | Active |
| Invox Pharma Limited | Corporate entity | Shares 75–100%, Voting 75–100% | 2023-03-08 | Ceased 2025-04-02 |
| F-Star Therapeutics Inc | Corporate entity | Shares 75–100%, Voting 75–100%, Appoints directors | 2020-11-20 | Ceased 2023-03-08 |
| Mr Tolga Hassan | Individual | Shares 75–100%, Voting 75–100%, Appoints directors | 2018-08-22 | Ceased 2019-05-07 |
Filing timeline
Last 20 of 88 total filings
Material constitutional events — rename, articles re-file, resolution
- 2026-04-17 RESOLUTIONS Resolution
- 2025-05-28 RESOLUTIONS Resolution
- 2025-05-27 MA Memorandum articles
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-04-18 | AA | accounts | Accounts with accounts type full | |
| 2026-04-17 | SH19 | capital | Capital statement capital company with date currency figure | |
| 2026-04-17 | SH20 | capital | Legacy | |
| 2026-04-17 | CAP-SS | insolvency | Legacy | |
| 2026-04-17 | RESOLUTIONS | resolution | Resolution | |
| 2025-12-10 | AD01 | address | Change registered office address company with date old address new address | |
| 2025-12-01 | TM01 | officers | Termination director company with name termination date | |
| 2025-10-20 | AA | accounts | Accounts with accounts type full | |
| 2025-08-23 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-07-24 | CH01 | officers | Change person director company with change date | |
| 2025-05-28 | RESOLUTIONS | resolution | Resolution | |
| 2025-05-27 | MA | incorporation | Memorandum articles | |
| 2025-04-07 | AP01 | officers | Appoint person director company with name date | |
| 2025-04-04 | PSC07 | persons-with-significant-control | Cessation of a person with significant control | |
| 2025-04-04 | PSC01 | persons-with-significant-control | Notification of a person with significant control | |
| 2025-04-04 | AP01 | officers | Appoint person director company with name date | |
| 2024-12-27 | AA | accounts | Accounts with accounts type full | |
| 2024-09-17 | MR04 | mortgage | Mortgage satisfy charge full | |
| 2024-08-28 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2023-09-29 | AA | accounts | Accounts with accounts type full |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 12
- Capital events
- 2
- Officers appointed
- 0
- Officers resigned
- 1
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.