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Cash

£45m

+186.3% vs 2024

Net assets

£23m

+348.9% vs 2024

Employees

55

-8.3% vs 2024

Profit before tax

£8.9m

+128.2% vs 2024

Accounts

2-year trend · Δ = latest vs prior filed period · latest reflected 2025-12-31

Metric Trend 2024-12-312025-12-31 Δ vs prior
Turnover £1,592,000£30,043,000 +1,787.1%
Operating profit -£31,840,000£7,943,000 +124.9%
Profit before tax -£31,345,000£8,851,000 +128.2%
Net profit -£27,511,000£8,309,000 +130.2%
Cash £15,584,000£44,612,000 +186.3%
Total assets less current liabilities £4,356,000£50,084,000 +1,049.8%
Net assets -£9,339,000£23,246,000 +348.9%
Equity -£9,339,000£23,246,000 +348.9%
Average employees 6055 -8.3%
Wages £6,153,000£4,709,000 -23.5%
Directors' remuneration £1,077,000£687,000 -36.2%
Directors' pension contributions £26,000£32,000 +23.1%
Highest paid director £666,000£635,000 -4.7%

Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. The Δ column is the change from the prior filed period as a percentage of |prior|; lines a company doesn't report show —. About these numbers

Ratios

Computed from the line items above — sparklines read oldest → newest

Ratio Trend 2024-12-312025-12-31
Operating margin —26.4%
Net margin —27.7%
Return on capital employed -730.9%15.9%
Gearing (liabilities / total assets) 141.6%58.2%
Current ratio 1.13x9.76x

Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Margin ratios are hidden where reported turnover is too small relative to profit to yield a meaningful figure — typical of holding companies whose income is mostly subsidiary dividends rather than trading revenue. Sector-distribution context coming next.

Audit & accounting basis

Accounting basis
FRS 102
Reporting scope
Consolidated group
Auditor
KPMG LLP
Audit opinion
Unqualified (clean)
Going concern
Affirmed

“The directors believe the Group has adequate cash positions and controls over future cashflow to allow the Group to continue for at least 12 months from the approval of the financial statements.”

Group structure

  1. ALCHEMAB THERAPEUTICS LTD · parent
    1. Alchemab, Inc 100% · USA · Biopharmaceutical development services

Significant events

Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers

People

7 active · 8 resigned

Name Role Appointed Born Nationality
GATES, Malcolm Derek Secretary 2026-03-05 — —
BINGHAM, Catherine Elizabeth, Dame Director 2023-07-26 Oct 1965 British
CIRCELLI, Carmine Daniel, Dr. Director 2026-06-17 Mar 1986 British
HEBERT, Jenna Director 2026-05-28 Mar 1994 American
LEE, Kevin Director 2021-06-30 Apr 1968 English
MAY, Andrew Paul, Dr Director 2026-06-04 Apr 1973 British
OSBOURN, Jane Katharine Director 2024-09-11 Mar 1966 British
Show 8 resigned officers
Name Role Appointed Resigned
ASHRAFIAN, Houman, Professor Director 2021-04-13 2023-07-26
COSTINE, James Allister John Director 2019-08-14 2021-04-13
DINES, Jonathon Alan Director 2019-08-14 2020-04-09
HAMER, John Director 2021-04-13 2026-06-04
KWON, Young T., Mr. Director 2022-05-25 2024-09-11
LEECH, Alexander Robert Director 2019-08-14 2021-04-13
LEVIN, Andrew David Director 2021-04-13 2026-05-21
TRECO, Douglas, Dr Director 2021-04-13 2022-04-22

Ownership

Persons with significant control

Name Kind Nature of control Notified Status
Sv7 (Imf) Gp Llp Corporate entity Shares 25–50% (as firm), Voting 25–50% (as firm) 2019-08-14 Ceased 2021-04-13
Dementia Discovery Gp Lp Corporate entity Shares 25–50%, Voting 25–50% 2019-08-14 Ceased 2020-04-02

Filing timeline

Last 20 of 92 total filings

Material constitutional events — rename, articles re-file, resolution

  • 2026-07-07 MA Memorandum articles
  • 2026-07-07 RESOLUTIONS Resolution
Date Type Category Description
2026-09-30 AA accounts Accounts with accounts type group
2026-07-14 SH01 capital Capital allotment shares PDF
2026-07-14 SH01 capital Capital allotment shares PDF
2026-07-07 MA incorporation Memorandum articles
2026-07-07 RESOLUTIONS resolution Resolution
2026-07-01 AP01 officers Appoint person director company with name date PDF
2026-06-23 AP01 officers Appoint person director company with name date PDF
2026-06-19 AP01 officers Appoint person director company with name date PDF
2026-06-19 TM01 officers Termination director company with name termination date PDF
2026-06-19 TM01 officers Termination director company with name termination date PDF
2026-03-10 CH03 officers Change person secretary company with change date PDF
2026-03-10 AP03 officers Appoint person secretary company with name date PDF
2025-12-12 CS01 confirmation-statement Confirmation statement with updates PDF
2025-11-20 SH01 capital Capital allotment shares PDF
2025-10-22 SH01 capital Capital allotment shares PDF
2025-10-02 AA accounts Accounts with accounts type medium
2025-08-28 SH01 capital Capital allotment shares PDF
2025-07-31 SH01 capital Capital allotment shares PDF
2025-07-28 SH08 capital Capital name of class of shares
2025-07-28 SH10 capital Capital variation of rights attached to shares

Public-record activity

Raw counts from Companies House — last 12–24 months

Filings
16

last 12 months

Capital events
8

last 24 months

Officers appointed
4

last 12 months

Officers resigned
2

last 12 months

Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.

Official Companies House page