T-CYPHER BIO HOLDINGS LIMITED
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Cash
£5.2M
-55.9% lowest in 3 filed years
Net assets
£6.7M
-49% lowest in 3 filed years
Employees
37
+15.6% highest in 3 filed years
Profit before tax
—
Period ending 2025-12-31
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
-
Material uncertainty over going concern
A material uncertainty exists over the successful completion of additional funding that may cast significant doubt on the company's ability to continue as a going concern. However, Directors expect adequate resources to continue in operational existence and meet liabilities for at least 12 months, and adopt the going concern basis.
-
Going-concern uncertainty disclosed
Net assets
3-year trend · vs Health Care median
Accounts
3-year trend · Δ = latest vs prior filed period · latest reflected 2025-12-31
| Metric | Trend | 2023-12-31 | 2024-12-31 | 2025-12-31 | Δ vs prior |
|---|---|---|---|---|---|
| Turnover | — | — | — | — | |
| Operating profit | — | — | — | — | |
| Profit before tax | — | — | — | — | |
| Net profit | — | — | — | — | |
| Cash | £5,858,239 | £11,874,908 | £5,242,396 | -55.9% | |
| Total assets less current liabilities | £6,960,824 | £13,222,597 | £6,748,390 | -49% | |
| Net assets | £6,960,824 | £13,222,597 | £6,748,390 | -49% | |
| Equity | £6,960,824 | £13,222,597 | £6,748,390 | -49% | |
| Average employees | 23 | 32 | 37 | +15.6% | |
| Wages | — | — | — | — | |
| Directors' remuneration | — | — | — | — |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. The Δ column is the change from the prior filed period as a percentage of |prior|; lines a company doesn't report show —. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2023-12-31 | 2024-12-31 | 2025-12-31 |
|---|---|---|---|---|
| Gearing (liabilities / total assets) | — | 8.2% | 14.3% | |
| Current ratio | 7.84x | 11.56x | 6.46x |
Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.
Audit & accounting basis
- Accounting basis
- FRS 102 §1A
- Reporting scope
- Consolidated group
- Abridged
- Yes — abridged accounts (limited disclosure)
- Auditor
- James Cowper Kreston Audit
- Audit opinion
- Unqualified (clean)
- Going concern
- Material uncertainty disclosed
“A material uncertainty exists over the successful completion of additional funding that may cast significant doubt on the company's ability to continue as a going concern. However, Directors expect adequate resources to continue in operational existence and meet liabilities for at least 12 months, and adopt the going concern basis.”
Group structure
- T-CYPHER BIO HOLDINGS LIMITED · parent
- T-Cypher Bio Limited 100%
- T-Cypher Bio US Inc 100%
Significant events
- “Subsequent to the year end, the Group agreed revised financing arrangements with existing investors in place of the originally anticipated final tranche funding under the Series A raise. These arrangements include a £3.9 million convertible loan note facility and an extension to the Series A funding round to secure additional equity funding. The Directors consider these arrangements supportive of the Group's ongoing funding requirements and have taken them into account in their going concern assessment.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
4 active · 7 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| BROWN, Claire, Dr | Director | 2021-08-25 | May 1971 | British |
| CLACKSON, Timothy Piers | Director | 2026-06-22 | Jun 1965 | British,American |
| HUGHES, Owen | Director | 2024-11-01 | Sep 1974 | American |
| MIR, Sohaib, Dr | Director | 2026-06-22 | Jan 1982 | British |
Show 7 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| ANDRESEN, Thomas Lars, Dr | Director | 2021-08-02 | 2026-03-15 |
| ASHTON, Christopher Philip | Director | 2023-01-04 | 2024-02-09 |
| FERNEAU, Philip James | Director | 2020-11-18 | 2023-06-29 |
| MARTIN, Barnaby Hugo Domnic | Director | 2020-11-18 | 2020-12-21 |
| MASRANI, Shyam | Director | 2023-06-29 | 2026-02-09 |
| OGG, Graham Stuart, Professor | Director | 2020-11-18 | 2023-06-29 |
| SCARLETT, Uciane | Director | 2020-08-28 | 2021-08-25 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Oxford Sciences Innovation Plc | Corporate entity | Shares 50–75%, Voting 50–75%, Appoints directors | 2020-08-28 | Active |
Filing timeline
Last 20 of 71 total filings
Material constitutional events — rename, articles re-file, resolution
- 2023-07-19 MA Memorandum articles
- 2023-07-19 RESOLUTIONS Resolution
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-06-30 | AP01 | officers | Appoint person director company with name date | |
| 2026-06-30 | AP01 | officers | Appoint person director company with name date | |
| 2026-06-24 | AA | accounts | Accounts with accounts type group | |
| 2026-06-18 | AD01 | address | Change registered office address company with date old address new address | |
| 2026-04-15 | TM01 | officers | Termination director company with name termination date | |
| 2026-02-17 | TM01 | officers | Termination director company with name termination date | |
| 2025-09-05 | AA | accounts | Accounts with accounts type group | |
| 2025-09-03 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-01-30 | SH01 | capital | Capital allotment shares | |
| 2025-01-30 | SH01 | capital | Capital allotment shares | |
| 2024-11-08 | AP01 | officers | Appoint person director company with name date | |
| 2024-09-09 | CS01 | confirmation-statement | Confirmation statement with no updates | |
| 2024-07-18 | AA | accounts | Accounts with accounts type small | |
| 2024-02-12 | TM01 | officers | Termination director company with name termination date | |
| 2023-08-04 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2023-08-03 | AA | accounts | Accounts with accounts type small | |
| 2023-07-19 | MA | incorporation | Memorandum articles | |
| 2023-07-19 | RESOLUTIONS | resolution | Resolution | |
| 2023-07-11 | AP01 | officers | Appoint person director company with name date | |
| 2023-07-11 | TM01 | officers | Termination director company with name termination date |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 8
- Capital events
- 2
- Officers appointed
- 2
- Officers resigned
- 2
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.