AMBER THERAPEUTICS HOLDINGS LIMITED
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Cash
£11m
-22.2% vs 2024
Net assets
£16m
-2.2% vs 2024
Employees
56
+133.3% highest in 4 filed years
Profit before tax
-£16m
-69.4% vs 2024
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
-
1 PSC ceased in last 24 months
Significant control changed hands — see the Ownership section.
Net assets
4-year trend · vs Health Care median
Accounts
4-year trend · Δ = latest vs prior filed period · latest reflected 2025-12-31
| Metric | Trend | 2021-12-31 | 2022-12-31 | 2024-12-31 | 2025-12-31 | Δ vs prior |
|---|---|---|---|---|---|---|
| Turnover | — | — | £436,822 | £99,556 | -77.2% | |
| Operating profit | — | — | -£9,722,083 | -£16,152,519 | -66.1% | |
| Profit before tax | — | — | -£9,332,573 | -£15,811,823 | -69.4% | |
| Net profit | — | — | -£8,142,201 | -£14,066,170 | -72.8% | |
| Cash | £498,684 | £194,670 | £13,651,887 | £10,620,353 | -22.2% | |
| Total assets less current liabilities | — | — | £17,091,897 | £16,737,404 | -2.1% | |
| Net assets | £499,108 | £196,977 | £16,221,369 | £15,871,399 | -2.2% | |
| Equity | £499,108 | £196,977 | £16,221,369 | £15,871,399 | -2.2% | |
| Average employees | 2 | 2 | 24 | 56 | +133.3% | |
| Wages | — | — | — | — | — | |
| Directors' remuneration | — | — | — | — | — |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. The Δ column is the change from the prior filed period as a percentage of |prior|; lines a company doesn't report show —. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2021-12-31 | 2022-12-31 | 2024-12-31 | 2025-12-31 |
|---|---|---|---|---|---|
| Return on capital employed | — | — | -56.9% | -96.5% | |
| Gearing (liabilities / total assets) | 1.1% | 3.1% | 9.3% | 14.2% | |
| Current ratio | — | — | 18.91x | 7.64x |
Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Margin ratios are hidden where reported turnover is too small relative to profit to yield a meaningful figure — typical of holding companies whose income is mostly subsidiary dividends rather than trading revenue. Sector-distribution context coming next.
Name history
Renamed 1 time since incorporation
- AMBER THERAPEUTICS HOLDINGS LIMITED 2024-07-11 → present
- AMBER THERAPEUTICS LTD 2020-12-18 → 2024-07-11
Audit & accounting basis
- Accounting basis
- FRS 102
- Reporting scope
- Consolidated group
- Auditor
- James Cowper Kreston Audit
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“The Directors, therefore, consider that it is appropriate to prepare the financial statements on a going concern basis.”
Group structure
- AMBER THERAPEUTICS HOLDINGS LIMITED · parent
- Amber Therapeutics Limited 100%
- Amber Therapeutics PTY Limited 100%
- Amber Therapeutics Ireland Limited 100%
- Amber Therapeutics Inc 100%
- Amber Therapeutics Canada Limited 100%
Significant events
- “During July 2026, after the year end, the Company issued 3,926,697 £0.001 Series A shares for a total consideration of £15,944,539. In addition, the Company issued 26,105 £0.001 Ordinary shares for a total consideration of £26.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
6 active · 2 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| AMERSON, David Rogers | Director | 2025-04-15 | Dec 1962 | American |
| BUTLER, Caroline | Director | 2024-05-23 | Feb 1980 | Irish |
| CHAMAS, Liliane, Doctor | Director | 2021-06-18 | Oct 1986 | British,Canadian |
| CHU, Yen-Min Kevin | Director | 2024-05-23 | Feb 1989 | Canadian |
| CRAWLEY, Aidan Harold Winston | Director | 2020-12-18 | Oct 1983 | British |
| LE, Tiffany | Director | 2024-05-23 | Jun 1990 | American |
Show 2 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| DENISON, Tim | Director | 2021-06-18 | 2024-05-23 |
| GLENN, Jonathan Martin | Director | 2023-12-01 | 2024-04-30 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Oxford Science Enterprises Holdings Ii Limited | Corporate entity | Shares 25–50%, Voting 25–50% | 2025-05-28 | Active |
| Oxford Science Enterprises Plc | Corporate entity | Shares 25–50%, Voting 25–50% | 2024-05-23 | Ceased 2025-05-28 |
| Aidan Harold Winston Crawley | Individual | Shares 75–100%, Voting 75–100%, Appoints directors | 2020-12-18 | Ceased 2021-06-18 |
Filing timeline
Last 20 of 66 total filings
Material constitutional events — rename, articles re-file, resolution
- 2026-07-22 MA Memorandum articles
- 2026-07-22 RESOLUTIONS Resolution
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-09-21 | AA | accounts | Accounts with accounts type group | |
| 2026-08-04 | SH01 | capital | Capital allotment shares | |
| 2026-07-22 | MA | incorporation | Memorandum articles | |
| 2026-07-22 | RESOLUTIONS | resolution | Resolution | |
| 2025-12-24 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-12-23 | PSC02 | persons-with-significant-control | Notification of a person with significant control | |
| 2025-12-23 | PSC07 | persons-with-significant-control | Cessation of a person with significant control | |
| 2025-12-18 | RP01AP01 | officers | Replacement filing of director appointment with name | |
| 2025-09-05 | AA | accounts | Accounts with accounts type group | |
| 2025-09-04 | SH01 | capital | Capital allotment shares | |
| 2025-09-04 | SH01 | capital | Capital allotment shares | |
| 2025-06-17 | AD01 | address | Change registered office address company with date old address new address | |
| 2025-06-16 | RP04SH01 | capital | Second filing capital allotment shares | |
| 2025-06-16 | RP04SH01 | capital | Second filing capital allotment shares | |
| 2025-06-16 | SH01 | capital | Capital allotment shares | |
| 2025-04-16 | SH01 | capital | Capital allotment shares | |
| 2025-04-16 | SH01 | capital | Capital allotment shares | |
| 2025-04-15 | AP01 | officers | Appoint person director company with name date | |
| 2025-02-04 | SH01 | capital | Capital allotment shares | |
| 2025-02-03 | RP04SH01 | capital | Second filing capital allotment shares |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 8
- Capital events
- 10
- Officers appointed
- 0
- Officers resigned
- 0
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.