CONSTRUCTIVE BIOLOGY LIMITED
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Next accounts due
2027-09-30 (in 1y)
Last filed for 2025-12-31
Confirmation statement due
2026-11-23 (in 6mo)
Last made up 2025-11-09
Watchouts
Cash
£45M
+44.2% vs 2024
Net assets
£48M
+44.8% vs 2024
Employees
46
+64.3% vs 2024
Profit before tax
-£2M
+73.9% vs 2024
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
-
2 PSCs ceased in last 24 months
Significant control changed hands — see the Ownership section.
Net assets
4-year trend · vs Health Care median
Accounts
4-year trend · latest reflected 2025-12-31
| Metric | Trend | 2022-11-30 | 2023-11-30 | 2024-12-31 | 2025-12-31 |
|---|---|---|---|---|---|
| Turnover | — | — | £0 | £10,779,441 | |
| Operating profit | — | — | -£6,486,397 | -£2,865,141 | |
| Profit before tax | — | — | -£6,022,327 | -£1,571,332 | |
| Net profit | — | — | -£5,630,765 | -£525,382 | |
| Cash | — | — | £31,361,373 | £45,230,269 | |
| Total assets less current liabilities | — | — | £33,129,664 | £47,985,975 | |
| Net assets | — | — | £33,129,664 | £47,985,975 | |
| Equity | — | £8,968,234 | £33,129,664 | £47,985,975 | |
| Average employees | — | — | 28 | 46 | |
| Wages | — | — | — | — | |
| Directors' remuneration | — | — | — | — |
Values shown as filed in the company's annual accounts. — indicates the figure wasn't present under that line item in that period. About these numbers
Year-on-year
FY2024 → FY2025 · period ending 2025-12-31 vs 2024-12-31
-
Turnover
—
Not reported
-
Cash
+44.2%
£31,361,373 £45,230,269
-
Net assets
+44.8%
£33,129,664 £47,985,975
-
Employees
+64.3%
28 46
-
Operating profit
+55.8%
-£6,486,397 -£2,865,141
-
Profit before tax
+73.9%
-£6,022,327 -£1,571,332
Each % is (latest − prior) ÷ |prior| for the line item as filed. The comparison is only shown when the latest and prior accounts cover broadly equal-length periods — short or long stubs (typical around incorporation or a year-end change) are suppressed rather than misrepresented. Lines a company doesn't report are omitted. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2022-11-30 | 2023-11-30 | 2024-12-31 | 2025-12-31 |
|---|---|---|---|---|---|
| Operating margin | — | — | — | -26.6% | |
| Net margin | — | — | — | -4.9% | |
| Return on capital employed | — | — | -19.6% | -6.0% | |
| Current ratio | — | — | 36.31x | 26.06x |
Margins divide P&L lines by turnover. Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Sector-distribution context coming next.
Name history
Renamed 1 time since incorporation
- CONSTRUCTIVE BIOLOGY LIMITED 2022-08-03 → present
- CONSTRUCTIVE GENOMICS LIMITED 2021-11-22 → 2022-08-03
Audit & accounting basis
- Accounting basis
- FRS 102
- Reporting scope
- Standalone (parent only)
- Abridged
- Yes — abridged accounts (limited disclosure)
- Auditor
- Ensors
- Audit opinion
- Unqualified (clean)
- Going concern
- Affirmed
“The directors have a reasonable expectation that the Company has adequate resources to continue in operational existence and to meet its financial obligations as they fall due for at least 12 months from the date of signing these financial statements. Accordingly, they continue to adopt the going concern basis in preparing the financial statements.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
8 active · 3 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| ELEMENTAL COMPANY SECRETARY LIMITED | Corporate Secretary | 2021-11-22 | — | — |
| CHIN, Jason William Karl, Dr | Director | 2021-11-22 | Jul 1973 | British |
| CONLEY, Paul | Director | 2022-05-13 | Mar 1968 | American |
| DHANDA, Rahul | Director | 2023-04-05 | Mar 1973 | American |
| KAMADOLLI, Shyam | Director | 2024-09-04 | Aug 1968 | American |
| WEISSMAN, James Barry | Director | 2026-04-24 | Feb 1962 | American |
| WINTER, Gregory Paul, Sir | Director | 2024-09-04 | Apr 1951 | British |
| WLODEK, Aleksandra Maria, Dr | Director | 2022-07-29 | Sep 1985 | Polish,British |
Show 3 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| NEWCOMBE-ELLIS, Matthew | Director | 2022-05-13 | 2024-09-04 |
| PEARCE, Jonathan James Hadow | Director | 2023-06-02 | 2024-09-04 |
| SOCHA, Pierre Robert | Director | 2022-05-13 | 2024-09-04 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Amadeus Capital Partners Limited | Corporate entity | Voting 25–50% | 2023-07-28 | Ceased 2024-09-04 |
| Amadeus V Technology Gp Lp | Corporate entity | Shares 25–50% | 2023-07-28 | Ceased 2024-09-04 |
| Dr Jason William Karl Chin | Individual | Shares 75–100%, Voting 75–100%, Appoints directors | 2021-11-22 | Ceased 2022-05-13 |
Filing timeline
Last 20 of 53 total filings
Material constitutional events — rename, articles re-file, resolution
- 2024-10-12 RESOLUTIONS Resolution
- 2024-09-29 RESOLUTIONS Resolution
- 2024-09-29 MA Memorandum articles
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-05-07 | AP01 | officers | Appoint person director company with name date | |
| 2026-04-16 | AA | accounts | Accounts with accounts type full | |
| 2026-02-26 | SH01 | capital | Capital allotment shares | |
| 2025-11-26 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-10-24 | SH01 | capital | Capital allotment shares | |
| 2025-10-24 | SH01 | capital | Capital allotment shares | |
| 2025-04-24 | AA | accounts | Accounts with accounts type small | |
| 2025-02-27 | SH01 | capital | Capital allotment shares | |
| 2025-02-19 | SH01 | capital | Capital allotment shares | |
| 2025-02-07 | SH01 | capital | Capital allotment shares | |
| 2025-02-07 | SH01 | capital | Capital allotment shares | |
| 2025-01-24 | SH01 | capital | Capital allotment shares | |
| 2024-11-21 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2024-11-04 | AA01 | accounts | Change account reference date company current extended | |
| 2024-10-12 | RESOLUTIONS | resolution | Resolution | |
| 2024-10-04 | SH01 | capital | Capital allotment shares | |
| 2024-09-29 | RESOLUTIONS | resolution | Resolution | |
| 2024-09-29 | MA | incorporation | Memorandum articles | |
| 2024-09-25 | PSC08 | persons-with-significant-control | Notification of a person with significant control statement | |
| 2024-09-25 | PSC07 | persons-with-significant-control | Cessation of a person with significant control |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 6
- Capital events
- 9
- Officers appointed
- 1
- Officers resigned
- 0
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.