BEACON THERAPEUTICS HOLDINGS LIMITED
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Cash
£63M
USD 84,312,826
+190.3% highest in 3 filed years
Net assets
£5.3M
USD 7,070,330
-70.4% lowest in 3 filed years
Employees
77
+8.5% vs 2024
Profit before tax
-£91M
USD -121,538,976
-54.2% lowest in 3 filed years
Watchouts
Facts from the Companies House register and the latest accounts — not a rating
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Material uncertainty over going concern
However, they acknowledge that there is a material uncertainty related to the Tranche 2 clinical milestone that may cast significant doubt on the Group's ability to continue as a going concern, therefore, the Group may be unable to realise its assets and discharge its liabilities in the normal course of business.
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Going-concern uncertainty disclosed
Net assets
3-year trend · vs Health Care median
Accounts
3-year trend · Δ = latest vs prior filed period · latest reflected 2025-12-31
| Metric | Trend | 2023-12-31 | 2024-12-31 | 2025-12-31 | Δ vs prior |
|---|---|---|---|---|---|
| Turnover | £223,798 | — | £112,292 | — | |
| Operating profit | -£49,607,622 | -£58,844,540 | -£91,267,981 | -55.1% | |
| Profit before tax | -£50,297,935 | -£59,018,943 | -£90,985,908 | -54.2% | |
| Net profit | -£49,082,262 | -£57,108,091 | -£88,241,068 | -54.5% | |
| Cash | £12,035,746 | £21,741,777 | £63,117,851 | +190.3% | |
| Total assets less current liabilities | £59,590,919 | £53,320,503 | £55,248,694 | +3.6% | |
| Net assets | £20,494,780 | £17,881,362 | £5,292,956 | -70.4% | |
| Equity | £20,494,780 | £17,881,362 | £5,292,956 | -70.4% | |
| Average employees | 88 | 71 | 77 | +8.5% | |
| Wages | £14,350,130 | £11,465,969 | £14,798,730 | +29.1% | |
| Directors' remuneration | £804,990 | £766,595 | £1,016,896 | +32.7% |
Figures converted to GBP from USD at 0.749 per USD (Frankfurter spot rate) — hover any figure for the original. — indicates the figure wasn't present under that line item in that period. The Δ column is the change from the prior filed period as a percentage of |prior|; lines a company doesn't report show —. About these numbers
Ratios
Computed from the line items above — sparklines read oldest → newest
| Ratio | Trend | 2023-12-31 | 2024-12-31 | 2025-12-31 |
|---|---|---|---|---|
| Return on capital employed | -83.2% | -110.4% | -165.2% | |
| Gearing (liabilities / total assets) | 70.3% | 70.2% | — | |
| Current ratio | 2.12x | 4.07x | 5.00x | |
| Interest cover | -54.58x | -76.72x | — |
Gearing is liabilities over total assets. Current ratio is current assets over creditors falling due within one year. Interest cover is operating profit over absolute finance costs. Margin ratios are hidden where reported turnover is too small relative to profit to yield a meaningful figure — typical of holding companies whose income is mostly subsidiary dividends rather than trading revenue. Sector-distribution context coming next.
Name history
Renamed 1 time since incorporation
- BEACON THERAPEUTICS HOLDINGS LIMITED 2023-06-01 → present
- SPL 123 LIMITED 2022-08-18 → 2023-06-01
Audit & accounting basis
- Accounting basis
- IFRS
- Reporting scope
- Consolidated group
- Auditor
- Grant Thornton UK LLP
- Audit opinion
- Unqualified (clean)
- Going concern
- Material uncertainty disclosed
“However, they acknowledge that there is a material uncertainty related to the Tranche 2 clinical milestone that may cast significant doubt on the Group's ability to continue as a going concern, therefore, the Group may be unable to realise its assets and discharge its liabilities in the normal course of business.”
Group structure
- BEACON THERAPEUTICS HOLDINGS LIMITED · parent
- Beacon Therapeutics Limited 100%
- Beacon Therapeutics (USA), Inc. 100%
Significant events
- “On 2 January 2026, the Group completed Series C Fund raising of $75m. $38.3m of this funding was received in advance in December 2025 and $2.7m was received in January 2026 with the balance expected to be received in the fourth quarter of 2026.”
Auditor, going-concern and subsidiary information is drawn from the narrative of the latest annual accounts. About these numbers
People
9 active · 4 resigned
| Name | Role | Appointed | Born | Nationality |
|---|---|---|---|---|
| BALDO, Lance | Director | 2024-10-03 | Oct 1972 | American |
| CHESTER, Cariad Dixon | Director | 2024-07-03 | Jul 1991 | American |
| FAROOQ, Khurem Arif | Director | 2023-05-01 | Feb 1967 | British |
| FELLOWS, David Andrew | Director | 2023-03-31 | Aug 1956 | American |
| HOLLOWOOD, Christopher John, Dr | Director | 2022-08-18 | Dec 1974 | British |
| HRISTODOROV, Dimitrij, Dr | Director | 2024-07-03 | May 1986 | German |
| JOUSTRA, Wouter Sebastian James | Director | 2024-07-03 | Jul 1988 | Dutch |
| PETRIS, Elisa Michela, Dr | Director | 2022-08-18 | Jan 1979 | Italian,Canadian |
| WALSH, Colin, Dr. | Director | 2025-12-23 | May 1985 | American |
Show 4 resigned officers
| Name | Role | Appointed | Resigned |
|---|---|---|---|
| JOHN, Markus Robert, Dr | Director | 2023-03-31 | 2024-07-03 |
| KAPLAN, Lester, Dr | Director | 2023-05-01 | 2025-12-21 |
| MACLAREN, Robert Edward, Dr | Director | 2023-03-31 | 2024-07-03 |
| SMIRNYAGINA, Ekaterina, Dr | Director | 2023-03-31 | 2024-07-03 |
Ownership
Persons with significant control
| Name | Kind | Nature of control | Notified | Status |
|---|---|---|---|---|
| Syncona Limited | Corporate entity | Shares 25–50%, Voting 25–50% | 2022-08-18 | Active |
Filing timeline
Last 20 of 59 total filings
Material constitutional events — rename, articles re-file, resolution
- 2026-02-04 RP04SH01 Legacy
- 2026-01-19 RP04SH01 Legacy
- 2026-01-05 RESOLUTIONS Resolution
- 2026-01-05 MA Memorandum articles
- 2025-11-03 RESOLUTIONS Resolution
- 2025-11-03 MA Memorandum articles
- 2025-04-30 MA Memorandum articles
- 2025-04-30 RESOLUTIONS Resolution
| Date | Type | Category | Description | |
|---|---|---|---|---|
| 2026-05-14 | AA | accounts | Accounts with accounts type group | |
| 2026-02-12 | SH01 | capital | Capital allotment shares | |
| 2026-02-04 | RP04SH01 | change-of-name | Legacy | |
| 2026-01-20 | SH01 | capital | Capital allotment shares | |
| 2026-01-19 | RP04SH01 | change-of-name | Legacy | |
| 2026-01-05 | TM01 | officers | Termination director company with name termination date | |
| 2026-01-05 | RESOLUTIONS | resolution | Resolution | |
| 2026-01-05 | MA | incorporation | Memorandum articles | |
| 2025-12-24 | AP01 | officers | Appoint person director company with name date | |
| 2025-11-06 | SH01 | capital | Capital allotment shares | |
| 2025-11-06 | PSC05 | persons-with-significant-control | Change to a person with significant control | |
| 2025-11-03 | RESOLUTIONS | resolution | Resolution | |
| 2025-11-03 | MA | incorporation | Memorandum articles | |
| 2025-08-26 | CS01 | confirmation-statement | Confirmation statement with updates | |
| 2025-06-06 | AA | accounts | Accounts with accounts type group | |
| 2025-05-16 | SH01 | capital | Capital allotment shares | |
| 2025-04-30 | MA | incorporation | Memorandum articles | |
| 2025-04-30 | RESOLUTIONS | resolution | Resolution | |
| 2024-10-16 | AA | accounts | Accounts with accounts type group | |
| 2024-10-15 | AP01 | officers | Appoint person director company with name date |
Public-record activity
Raw counts from Companies House — last 12–24 months
- Filings
- 14
- Capital events
- 4
- Officers appointed
- 1
- Officers resigned
- 1
last 12 months
last 24 months
last 12 months
last 12 months
Direct counts from the register. No score, no rating — see the Filing timeline for the underlying events.