| 01 | WELLCOME TRUST | £1.41bn | £589m |
| 02 | THE CHARITIES AID FOUNDATION | £1.14bn | £1.39bn |
| 03 | THE CHILDREN'S INVESTMENT FUND FOUNDATION (UK) | £473m | £66.7m |
| 04 | CANCER RESEARCH UK | £307m | £735m |
| 05 | GREAT ORMOND STREET HOSPITAL CHILDREN'S CHARITY | £297m | £140m |
| 06 | SAVE THE CHILDREN INTERNATIONAL | £292m | £1.10bn |
| 07 | INTERNATIONAL FINANCE FACILITY FOR IMMUNISATION COMPANY | £286m | £36.8m |
| 08 | THE ARTS COUNCIL OF ENGLAND | £261m | £843m |
| 09 | CHURCH COMMISSIONERS FOR ENGLAND | £241m | £207m |
| 10 | UBS UK Donor-Advised Foundation | £230m | £181m |
| 11 | QUADRATURE CLIMATE FOUNDATION | £205m | £222m |
| 12 | THE ARCHBISHOPS' COUNCIL | £192m | £235m |
| 13 | CITB | £178m | £280m |
| 14 | THE MASTER CHARITABLE TRUST | £173m | £155m |
| 15 | THE SAVE THE CHILDREN FUND | £154m | £263m |
| 16 | Founders Pledge Ltd | £149m | £246m |
| 17 | UBS OPTIMUS FOUNDATION UK | £144m | £157m |
| 18 | THE LEVERHULME TRUST | £131m | £124m |
| 19 | GARFIELD WESTON FOUNDATION | £128m | £165m |
| 20 | SOUTHAMPTON ROW TRUST LIMITED | £122m | £147m |
| 21 | THE GATSBY CHARITABLE FOUNDATION | £120m | £95.5m |
| 22 | THE FOOTBALL FOUNDATION | £106m | £128m |
| 23 | THE CH FOUNDATION (UK) | £100m | £119m |
| 24 | CHURCH OF ENGLAND CENTRAL SERVICES | £99.9m | £131m |
| 25 | PARISH GIVING SCHEME | £99.9m | £103m |
| 26 | BRITISH HEART FOUNDATION | £98.6m | £411m |
| 27 | AKO FOUNDATION | £85.3m | £70.2m |
| 28 | THE BRITISH ACADEMY FOR THE PROMOTION OF HISTORICAL PHILOSOPHICAL AND PHILOLOGICAL STUDIES | £85.0m | £106m |
| 29 | NPT Transatlantic Limited | £84.3m | £84.3m |
| 30 | THE UNITED KINGDOM COMMITTEE FOR UNICEF | £84.0m | £135m |
| 31 | THE BRITISH RED CROSS SOCIETY | £82.9m | £287m |
| 32 | BRIDGE HOUSE ESTATES | £78.9m | £42.6m |
| 33 | ACHISOMOCH AID COMPANY LIMITED | £71.2m | £73.8m |
| 34 | OXFAM | £67.3m | £339m |
| 35 | Walk Wheel Cycle Trust | £67.3m | £111m |
| 36 | PAYPAL GIVING FUND UK | £63.7m | £66.6m |
| 37 | THE HENRY SMITH CHARITY | £60.1m | £16.4m |
| 38 | THE BRITISH COUNCIL | £59.0m | £1.01bn |
| 39 | MEDECINS SANS FRONTIERES (UK) | £56.6m | £95.3m |
| 40 | AGA KHAN FOUNDATION (UNITED KINGDOM) | £54.1m | £91.3m |
| 41 | CARE INTERNATIONAL UK | £53.7m | £64.1m |
| 42 | INTERNATIONAL PLANNED PARENTHOOD FEDERATION | £53.2m | £97.7m |
| 43 | ESMEE FAIRBAIRN FOUNDATION | £52.7m | £8.9m |
| 44 | WORLD VISION UK | £52.6m | £66.1m |
| 45 | THE GRACE TRUST | £52.4m | £60.7m |
| 46 | BREAKTHROUGH FOUNDATION | £51.6m | £50.0m |
| 47 | MACMILLAN CANCER SUPPORT | £46.5m | £246m |
| 48 | National Philanthropic Trust UK Limited | £43.0m | £225m |
| 49 | ST PETER'S COLLEGE (OTHERWISE KNOWN AS WESTMINSTER SCHOOL) | £42.8m | £46.1m |
| 50 | THE FEDERATION OF GROUNDWORK TRUSTS | £40.6m | £48.7m |
| 51 | THE KATHERINE MARTIN CHARITABLE TRUST | £39.3m | £2.5m |
| 52 | COMPASSION UK CHRISTIAN CHILD DEVELOPMENT | £38.8m | £53.2m |
| 53 | UK DRI LTD | £38.5m | £47.6m |
| 54 | BBC CHILDREN IN NEED | £37.6m | £61.0m |
| 55 | THE WOLFSON FOUNDATION | £37.2m | £26.9m |
| 56 | ENGLAND AND WALES CRICKET TRUST | £36.7m | £41.7m |
| 57 | NATIONAL ASSISTANCE FUND | £35.8m | £41.8m |
| 58 | THE BOLOGNA CENTER OF THE JOHNS HOPKINS UNIVERSITY CHARITABLE TRUST | £35.8m | £9k |
| 59 | PAUL HAMLYN FOUNDATION | £34.4m | £50.7m |
| 60 | PLAN INTERNATIONAL UK | £34.2m | £61.7m |
| 61 | WWF - UK | £34.2m | £89.3m |
| 62 | THE ROYAL ACADEMY OF ENGINEERING | £34.2m | £71.8m |
| 63 | LIFEARC | £33.5m | £86.7m |
| 64 | DAWAT-E-HADIYAH TRUST (UNITED KINGDOM) | £33.2m | £44.1m |
| 65 | GUY'S AND ST THOMAS' FOUNDATION | £32.8m | £34.3m |
| 66 | IMPETUS - THE PRIVATE EQUITY FOUNDATION | £32.1m | £24.1m |
| 67 | CYNGOR CELFYDDYDAU CYMRU | £31.0m | £57.7m |
| 68 | CHARITY PROJECTS | £30.7m | £51.1m |
| 69 | MOONDANCE FOUNDATION | £30.7m | £66.4m |
| 70 | THE FEBRUARY FOUNDATION | £30.5m | £34.3m |
| 71 | AMANAT CHARITY TRUST | £30.3m | £71.9m |
| 72 | MUSLIM HANDS | £29.7m | £33.4m |
| 73 | ACTIONAID | £29.3m | £47.6m |
| 74 | WALES COUNCIL FOR VOLUNTARY ACTION | £29.3m | £36.6m |
| 75 | CHRISTIAN AID | £28.9m | £71.4m |
| 76 | THE FARADAY INSTITUTION | £28.8m | £33.3m |
| 77 | AGE UK | £28.6m | £132m |
| 78 | PILKINGTON CHARITIES FUND | £28.6m | £645k |
| 79 | ARMED FORCES COVENANT FUND | £28.4m | £30.9m |
| 80 | GOLDMAN SACHS GIVES (UK) | £28.0m | £27.5m |
| 81 | THE PEARS FAMILY CHARITABLE FOUNDATION | £27.6m | £28.5m |
| 82 | ROYAL COMMONWEALTH SOCIETY FOR THE BLIND | £26.8m | £286m |
| 83 | THE YOUTH ENDOWMENT FUND CHARITABLE TRUST | £26.4m | £11.5m |
| 84 | CATHOLIC AGENCY FOR OVERSEAS DEVELOPMENT | £25.8m | £56.2m |
| 85 | HOSPICE UK | £25.8m | £34.1m |
| 86 | ENGINEERING CONSTRUCTION INDUSTRY TRAINING BOARD | £25.7m | £38.8m |
| 87 | ALZHEIMER'S RESEARCH UK | £25.4m | £61.9m |
| 88 | BENEFACT TRUST LIMITED | £25.4m | £48.9m |
| 89 | ONE UMMAH | £24.7m | £24.4m |
| 90 | HUMAN APPEAL | £24.5m | £90.2m |
| 91 | LLOYDS BANK FOUNDATION FOR ENGLAND & WALES | £24.4m | £29.6m |
| 92 | THE TRUSSELL TRUST | £24.0m | £62.8m |
| 93 | UNITED BIBLE SOCIETIES ASSOCIATION | £24.0m | £35.0m |
| 94 | MOTABILITY | £23.5m | £54.2m |
| 95 | THE CONGREGATION OF THE DAUGHTERS OF THE CROSS OF LIEGE | £22.1m | £16.0m |
| 96 | THE CALLEVA FOUNDATION | £21.8m | £12.6m |
| 97 | THE EDUCATION ENDOWMENT FOUNDATION | £21.8m | £52.4m |
| 98 | THE SALVATION ARMY INTERNATIONAL TRUST | £21.8m | £81.8m |
| 99 | ORPHANS IN NEED | £20.9m | £23.5m |
| 100 | UNIVERSITY COLLEGE LONDON HOSPITALS CHARITY | £20.7m | £24.7m |
