| 01 | WELLCOME TRUST | £477m | £569m |
| 02 | CHURCH COMMISSIONERS FOR ENGLAND | £204m | £207m |
| 03 | GARFIELD WESTON FOUNDATION | £165m | £165m |
| 04 | THE LEVERHULME TRUST | £104m | £104m |
| 05 | THE CHARITIES AID FOUNDATION | £100m | £1.39bn |
| 06 | TRINITY COLLEGE CAMBRIDGE | £83.5m | £106m |
| 07 | THE CHILDREN'S INVESTMENT FUND FOUNDATION (UK) | £66.7m | £66.7m |
| 08 | REUBEN FOUNDATION | £63.5m | £64.3m |
| 09 | MOTABILITY | £52.4m | £54.2m |
| 10 | SUTL CAZENOVE CHARITY NON-UCITS FUND | £50.8m | £50.8m |
| 11 | CANAL & RIVER TRUST | £50.6m | £233m |
| 12 | THE EQUITIES INVESTMENT FUND FOR CHARITIES (CHARIFUND) | £48.0m | £48.0m |
| 13 | THE ALBERT GUBAY CHARITABLE FOUNDATION | £47.9m | £55.4m |
| 14 | MOONDANCE FOUNDATION | £41.5m | £66.4m |
| 15 | BLACKROCK CHARITIES FUNDS | £37.2m | £37.2m |
| 16 | INTERNATIONAL FINANCE FACILITY FOR IMMUNISATION COMPANY | £35.9m | £36.8m |
| 17 | BENEFACT TRUST LIMITED | £35.8m | £48.9m |
| 18 | THE COLLEGE OF ST MARY MAGDALEN IN THE UNIVERSITY OF OXFORD | £32.8m | £53.5m |
| 19 | BRIDGE HOUSE ESTATES | £31.2m | £42.6m |
| 20 | ST JOHN'S COLLEGE CAMBRIDGE | £29.3m | £58.7m |
| 21 | GUY'S AND ST THOMAS' FOUNDATION | £27.4m | £34.3m |
| 22 | THE DEAN AND CHAPTER OF THE CATHEDRAL CHURCH OF CHRIST IN OXFORD OF THE FOUNDATION OF KING HENRY VIII | £27.1m | £50.0m |
| 23 | THE WOLFSON FOUNDATION | £26.9m | £26.9m |
| 24 | CHRISTIAN VISION | £26.4m | £31.5m |
| 25 | SAINT JOHN BAPTIST COLLEGE IN THE UNIVERSITY OF OXFORD | £24.2m | £35.4m |
| 26 | THE ROTHERWICK FOUNDATION | £24.2m | £24.2m |
| 27 | THE HELPING FOUNDATION | £23.6m | £34.8m |
| 28 | THE KYNGE'S COLLEGE OF OUR LADYE OF ETON BESYDE WINDESORE | £23.4m | £99.6m |
| 29 | THE GATSBY CHARITABLE FOUNDATION | £22.5m | £95.5m |
| 30 | LLOYD'S REGISTER FOUNDATION | £22.0m | £692m |
| 31 | THE ROYAL SOCIETY OF LONDON FOR IMPROVING NATURAL KNOWLEDGE (COMMONLY KNOWN AS THE ROYAL SOCIETY) | £21.9m | £158m |
| 32 | THE REPRESENTATIVE BODY OF THE CHURCH IN WALES | £21.2m | £22.0m |
| 33 | LIFEARC | £20.5m | £205m |
| 34 | SOCIETY OF JESUS TRUST OF 1929 FOR ROMAN CATHOLIC PURPOSES | £18.9m | £48.9m |
| 35 | THE COLLEGE OF ALL SOULS OF THE FAITHFUL DEPARTED, OF OXFORD | £18.5m | £19.2m |
| 36 | A W CHARITABLE TRUST | £17.6m | £17.6m |
| 37 | THE NESTA TRUST | £17.3m | £17.3m |
| 38 | CHARITY ASSETS TRUST | £17.3m | £17.3m |
| 39 | DELAPAGE LIMITED | £16.6m | £19.7m |
| 40 | THE ROTHSCHILD FOUNDATION | £16.2m | £27.2m |
| 41 | THE HENRY SMITH CHARITY | £16.2m | £16.4m |
| 42 | NESTA | £15.0m | £55.3m |
| 43 | THE HEALTH FOUNDATION | £14.9m | £17.2m |
| 44 | THE MERCHANT TAYLORS' BOONE'S CHARITY | £14.8m | £2.0m |
| 45 | THE DULWICH ESTATE | £14.6m | £14.6m |
| 46 | DENISE COATES FOUNDATION | £14.0m | £144m |
| 47 | CHRIST'S HOSPITAL FOUNDATION | £13.2m | £20.0m |
| 48 | CHRIST'S HOSPITAL | £13.2m | £56.4m |
| 49 | MORDEN COLLEGE | £12.7m | £16.1m |
| 50 | THE ARTS COUNCIL OF ENGLAND | £12.1m | £843m |
| 51 | NUFFIELD COLLEGE IN THE UNIVERSITY OF OXFORD | £11.9m | £14.0m |
| 52 | MASONIC CHARITABLE FOUNDATION | £11.7m | £90.8m |
| 53 | JOHN LYON'S CHARITY | £11.5m | £11.5m |
| 54 | UBS UK Donor-Advised Foundation | £11.1m | £181m |
| 55 | MILTON KEYNES PARKS TRUST LIMITED | £11.1m | £17.9m |
| 56 | THE KENNEDY TRUST FOR RHEUMATOLOGY RESEARCH | £10.9m | £11.3m |
| 57 | GREAT ORMOND STREET HOSPITAL CHILDREN'S CHARITY | £10.8m | £140m |
| 58 | THE MASTER CHARITABLE TRUST | £10.6m | £108m |
| 59 | CARDIFF UNIVERSITY | £10.5m | £634m |
| 60 | THE CLOTHWORKERS' FOUNDATION | £10.4m | £12.3m |
| 61 | THE BRITISH COUNCIL | £10.4m | £1.01bn |
| 62 | THE QUEEN'S COLLEGE, OXFORD | £10.2m | £19.9m |
| 63 | ST MONICA TRUST | £10.2m | £53.7m |
| 64 | BRITISH HEART FOUNDATION | £10.0m | £411m |
| 65 | WESTMINSTER ROMAN CATHOLIC DIOCESAN TRUST AND OTHER TRUST FUNDS ADMINISTERED BY THE WESTMINSTER ROMAN CATHOLIC DIOCESAN TRUSTEE | £9.9m | £75.1m |
| 66 | THE RAPHAEL FRESHWATER MEMORIAL ASSOCIATION | £9.7m | £11.7m |
| 67 | BARTS CHARITY | £9.7m | £12.9m |
| 68 | GREENHAM TRUST LTD | £9.6m | £16.3m |
| 69 | THE AGAINST MALARIA FOUNDATION | £9.5m | £114m |
| 70 | FIA FOUNDATION | £9.5m | £9.5m |
| 71 | THE CORPORATION OF TRINITY HOUSE OF DEPTFORD STROND | £9.5m | £13.5m |
| 72 | PAUL HAMLYN FOUNDATION | £9.4m | £50.7m |
| 73 | M&G MULTI-ASSET FUND FOR CHARITIES | £9.4m | £9.4m |
| 74 | SHLOMO MEMORIAL FUND LIMITED | £9.3m | £10.2m |
| 75 | GONVILLE AND CAIUS COLLEGE IN THE UNIVERSITY OF CAMBRIDGE FOUNDED IN HONOUR OF THE ANNUNCIATION OF THE BLESSED MARY THE VIRGIN | £9.2m | £26.4m |
| 76 | THE ROYAL BRITISH LEGION | £9.2m | £168m |
| 77 | THE SALVATION ARMY | £9.1m | £338m |
| 78 | ESMEE FAIRBAIRN FOUNDATION | £9.0m | £9.5m |
| 79 | THE KING'S HALL AND COLLEGE OF BRASENOSE IN OXFORD | £9.0m | £18.3m |
| 80 | MSI REPRODUCTIVE CHOICES | £9.0m | £310m |
| 81 | THE WATERLOO FOUNDATION | £8.9m | £15.5m |
| 82 | THE WHITGIFT FOUNDATION | £8.8m | £77.1m |
| 83 | THE NATIONAL TRUST FOR PLACES OF HISTORIC INTEREST OR NATURAL BEAUTY | £8.6m | £766m |
| 84 | THE TUDOR TRUST | £8.5m | £8.5m |
| 85 | THE WARDEN AND SCHOLARS OF ST MARY COLLEGE OF WINCHESTER | £8.5m | £45.9m |
| 86 | THE WARDEN AND SCHOLARS OF THE HOUSE OR COLLEGE OF SCHOLARS OF MERTON IN THE UNIVERSITY OF OXFORD | £8.5m | £20.4m |
| 87 | Becht Foundation | £8.4m | £8.5m |
| 88 | SHELL FOUNDATION | £8.3m | £29.3m |
| 89 | UNIVERSITY OF SOUTH WALES/PRIFYSGOL DE CYMRU | £8.2m | £225m |
| 90 | THE NUFFIELD FOUNDATION | £8.2m | £14.3m |
| 91 | SAVE THE CHILDREN INTERNATIONAL | £8.1m | £1.10bn |
| 92 | CANCER RESEARCH UK | £8.1m | £735m |
| 93 | The Portal Trust | £8.1m | £8.2m |
| 94 | THE EXILARCH'S FOUNDATION | £8.0m | £8.0m |
| 95 | THE MASTER FELLOWS AND SCHOLARS OF EMMANUEL COLLEGE IN THE UNIVERSITY OF CAMBRIDGE | £7.9m | £22.9m |
| 96 | JESUS COLLEGE IN THE UNIVERSITY OF CAMBRIDGE | £7.9m | £31.1m |
| 97 | THE RUMI FOUNDATION | £7.9m | £9.0m |
| 98 | THE LAND RESTORATION TRUST | £7.8m | £10.3m |
| 99 | THE MASTER (OR KEEPER) AND FELLOWS OF PETERHOUSE IN THE UNIVERSITY OF CAMBRIDGE | £7.8m | £16.4m |
| 100 | WS Epworth Investment Funds for Charities | £7.7m | £47.0m |
